chlorobis(N,N-dimethyldithiocarbamato-S,S')antimony(III) | 194411-44-4

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: chlorobis(N,N-dimethyldithiocarbamato-S,S')antimony(III)
• 英文别名: bis(N,N'-dimethyldithiocarbamato-S,S')antimony(III) chloride；chloroantimony(III) bis(dimethyldithiocarbamate)；antimony(III) bis(dimethyldithiocarbamate) chloride；[chloro(dimethylcarbamothioylsulfanyl)stibanyl] N,N-dimethylcarbamodithioate
• CAS: 194411-44-4
• 化学式: C₆H₁₂ClN₂S₄Sb
• 分子量: 397.642
• InChiKey: AAZWBVNYALBRLA-UHFFFAOYSA-K

计算性质

• 辛醇/水分配系数(LogP)：
  2.37
• 重原子数：
  14.0
• 可旋转键数：
  0.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  6.48
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  chlorobis(N,N-dimethyldithiocarbamato-S,S')antimony(III) 、 异丁基黄原酸钾 以 二硫化碳 、 苯 为溶剂， 以80%的产率得到antimony(III) bis(dimethyldithiocarbamato)isobutyldithiocarbonate
  参考文献：
  名称：

  锑（III）双（二烷基二硫代氨基甲酸酯）烷基二硫代碳酸酯的合成，光谱表征和抗菌活性。

  摘要：

  通式[[R（2）NCS（2））]（2）SbS（2）COR'的锑的一些硫供体配体配合物，其中R = CH（3），C（2）H（ 5）和R'= Me，Et，Pr（n），Pr（i），Bu（n）和Bu（i）是通过氯化锑（III）双（二烷基二硫代氨基甲酸酯）氯化物与有机二硫代碳酸钾反应制得的通过在室温下在苯/ CS（2）混合物中搅拌得到等摩尔比。这些配合物的特征是通过理化[元素分析，熔点和分子量测定]和光谱[UV，IR，远红外，NMR（（1）H和（13）C），FAB（+）质量和粉末X -射线衍射]研究。还针对不同的细菌菌株筛选了游离配体和合成的复合物，并且获得的结果使得有必要描述游离配体之间的比较，

  DOI：

  10.1016/j.saa.2011.06.031

文献信息

• Synthetic aspects, spectral, thermal studies and antimicrobial screening on bis(N,N-dimethyldithiocarbamato-S,S′)antimony(III) complexes with oxo or thio donor ligands
  作者：H.P.S. Chauhan、Jaswant Carpenter、Sapana Joshi

  DOI：10.1016/j.saa.2014.03.054

  日期：2014.9

  elemental analysis (C, H, N, S and Sb)], spectral [UV–Visible, FT-IR, far IR, NMR (1H and 13C)], thermogravimetric (TG & DTA) analysis, ESI-Mass and powder X-ray diffraction studies. Thermogravimetric analysis of the complexes confirmed the final decomposition product as highly pure antimony sulfide (Sb2S3) and powder X-ray diffraction studies show that the complexes are in lower symmetry with monoclinic

  的双（Ñ，Ñ -dimethyldithiocarbamato-小号，小号'）锑（III）配合物已经被氯的反应获得的双（Ñ，Ñ -dimethyldithiocarbamato-小号，小号'）锑（III）与相应的氧代或硫代施主配体如苯甲酸钠1，巯基乙酸钠2，苯酚3，钠1-丙硫醇4，硫代乙酸钾5，水杨酸钠6，乙烷-1,2-二硫醇7和草酸二钠8。这些配合物的特征是通过物理化学[熔点，分子量测定和元素分析（C，H，N，S和Sb）]，光谱[UV-Visible，FT-IR，远红外，NMR（1 H和13 C）]，热重分析（TG＆DTA），ESI质量和粉末X射线衍射研究。配合物的热重分析证实最终分解产物为高纯硫化锑（Sb 2 S 3）和粉末X射线衍射研究表明，该配合物的对称性较低，具有单斜晶格和纳米级粒径（11.51–20.82 nm）。还针对某些细菌和真菌菌株筛选了复合物的抗菌和抗真菌活性，并与标准
• Preparation, spectroscopic characterization and antimicrobial activities of mixed metal (Sb and Bi) bridged derivatives with mixed sulfur donor ligands
  作者：Sapana Joshi、H.P.S. Chauhan、Nitin Carpenter

  DOI：10.1016/j.molstruc.2016.08.063

  日期：2017.1

  Abstract This article explores the syntheses of six mixed metal derivatives of antimony(III) and bismuth(III) by the reaction of ethane-1,2-dithiol and metal bis derivatives of dithiocarbamates and/or dithiophosphates ligands in 1:1:1 M stoichiometry. These derivatives have been characterized by physicochemical [elemental analysis (C, H, N, S, Sb and Bi), molecular weight and melting point determinations]

  摘要 本文探讨了通过乙烷-1,2-二硫醇与二硫代氨基甲酸盐和/或二硫代磷酸盐配体的金属双衍生物在 1:1:1 M 中反应合成锑 (III) 和铋 (III) 的六种混合金属衍生物。化学计量。这些衍生物已通过物理化学 [元素分析（C、H、N、S、Sb 和 Bi）、分子量和熔点测定]、光谱 [UV-Visible、FTIR、NMR（ 1 H、 13 C 和 31 P )]，粉末 X 射线衍射研究。这些衍生物具有纳米范围的微晶尺寸（8.18-18.04 nm），具有单斜晶系。所有合成的衍生物都有两个金属中心（Sb 和 Bi），与单一金属种类（金属前体）和标准药物相比，它们提高了对四种细菌和两种真菌种类的抑制区域。
• SYNTHESIS AND CHARACTERIZATION OF SOME DITHIOLATOANTIMONY(III) DIALKYLDITHIOCARBAMATES
  作者：S. Chourasia、B. Nahar、H. P. S. Chauhan

  DOI：10.1080/10426509608043466

  日期：1996.12

  yielded compounds of the type (R2NCS2)2Sb-SCH2-CH2S-Sb (S2CNR2)2 [where R = Me, Et and R2 = (CH2)4]. These newly synthesised derivatives are soluble in organic solvents like benzene, chloroform and carbon tetrachloride. These derivatives have been characterised by elemental analysis (C. H, N, Sb and S). melting points as well as IR, 1H NMR and 13C NMR spectral studies.

  摘要 乙烷-1,2-二硫代氯化锑和甲苯-3,4-二硫代氯化锑与摩尔比为 1:1 的二烷基二硫代氨基甲酸钠在无水苯中的置换反应产生 [其中 R = Me , Et 和 R2 = (CH2)+1，和 -AA- = - - - 和 。氯锑 (III) 双（二烷基二硫代氨基甲酸酯）和二硫醇钠在无水苯中以 2:1 的摩尔比反应生成 (R2NCS2)2Sb-S - S-Sb (S2CNR2)2 类型的化合物 [其中 R = Me、Et 和 R2 = ( )4]。这些新合成的衍生物可溶于苯、氯仿和​​四氯化碳等有机溶剂。这些衍生物已通过元素分析（C. H、N、Sb 和 S）进行了表征。熔点以及 IR、1H NMR 和 13C NMR 光谱研究。
• Synthesis, characterization and biological activity of antimony(III) or bismuth(III) chloride complexes with dithiocarbamate ligands derived from thiuram degradation
  作者：I.I. Ozturk、C.N. Banti、N. Kourkoumelis、M.J. Manos、A.J. Tasiopoulos、A.M. Owczarzak、M. Kubicki、S.K. Hadjikakou

  DOI：10.1016/j.poly.2013.08.052

  日期：2014.1

  Antimony(III) or bismuth(III) complexes of formulae [SbCI(Me2DTC)(2)](n)} (I), [BiCl(Me2DTC)(2)](n)} (2) and [Bi(Et2DTC)(3)](2)} (3) (Me2DTCH = dimethyldithiocarbamate, C3H7NS2 and Et2DTCH = diethyldithiocarbamate, C-5-H11NS2) were isolated from the reactions between SbCl3 or BiCl3 with tetramethylthiuram monosulfide (Me(4)tms), tetramethylthiuram disulfide (Me(4)tds) or tetraethylthiuram disulfide (Et(4)tds). In the case of 1 two polymorphs were isolated depending on the synthetic procedure followed. Crystal growth from the reaction of antimony(III)-chloride with Me(4)tms in methanol produced la polymorph, while those derived from Me(4)tds in acetonitrile/dichloromethane produced lb form. The complexes 1-3 were characterized by m.p., e.a., FT-IR, FT-Raman, H-1, C-13 NMR spectroscopy and Thermal Gravimetry-Differential Thermal Analysis (TGA-DTA). Moreover, single crystal X-ray diffraction analysis was carried out for 1a, 2b, 2 and 3. X-ray powder diffraction data confirm the existence of one polymorph in the bulk of each sample of 1a and 1b. H-1 NMR spectra in the DMSO-d(6) solutions of 1a and 1b suggest the retention of the structural variations. Complexes 1 and 2 are polymers with distorted square pyramidal (SPY) geometry in each monomeric unit. The known structure of 3 was re-determined to be used for the theoretical and structure activity relationship studies (SAR).Complexes 1-3 were evaluated for their in vitro cytotoxic activity against human breast adenocarcinoma (MCF-7) and human cervix adenocarcinoma (HeLa) cells. Complex 3 is more active against HeLa cells whereas 1a, 1b and 2 against MCF-7. Compound la shows slightly higher activity than lb. Principal components analysis (PCA) was performed to discriminate the significant physicochemical molecular descriptors while regression analysis successfully related the experimental inhibitory concentration, (IC50) to the independent variables indexed by PCA. The calculated IC50 values are satisfactorily compared with the measured inhibitory activity of the complexes. (C) 2013 Elsevier Ltd. All rights reserved.
• Egle, R.; Klinkhammer, W.; Schmidt, A., Zeitschrift fur Anorganische und Allgemeine Chemie
  作者：Egle, R.、Klinkhammer, W.、Schmidt, A.

  DOI：——

  日期：——