2-Chlor-10-(4-methylpiperazino)-10,11-dihydro-dibenzothiepin | 4789-63-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并硫平类
• 英文名称: 2-Chlor-10-(4-methylpiperazino)-10,11-dihydro-dibenzothiepin
• 英文别名: 1-(2-chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine；2-Chloro-10-(4-methylpiperazino)-10,11-dihydrodibenzo(b,f)thiepin；1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-6-yl)-4-methylpiperazine
• CAS: 4789-63-3
• 化学式: C₁₉H₂₁ClN₂S
• 分子量: 344.908
• InChiKey: RGQQPQPTXXRIIN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  23
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  31.8
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] METHODS AND COMPOSITIONS FOR THE TREATMENT OF SARS-COV-2<br/>[FR] MÉTHODES ET COMPOSITIONS POUR LE TRAITEMENT DU SARS-COV 2
  申请人：SCRIPPS RESEARCH INST

  公开号：WO2021225767A1

  公开（公告）日：2021-11-11

  Disclosed herein are methods that are useful for treating a subject who has a pathogenic infection, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); reducing the likelihood of the subject from being infected by a pathogen; and for reducing the transmission of a pathogen from a subject to others. The methods utilize a compound disclosed in Table 1 or Table 4 herein, optionally in combination with an additional agent such as an anti-infective agent.