[(2R,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methyl [(2R,3R,4S,5R)-6-[[(2S,3R,4R,5S)-6-[(2R,3R,4R,5S)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-3,4,5-trihydroxyoxan-2-yl]methyl hydrogen phosphate

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷酸
• 英文名称: [(2R,5R)-5-(6-aminopurin-9-yl)-3-hydroxyoxolan-2-yl]methyl [(2R,3R,4S,5R)-6-[[(2S,3R,4R,5S)-6-[(2R,3R,4R,5S)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-3,4,5-trihydroxyoxan-2-yl]methyl hydrogen phosphate
• 化学式: C₂₈H₄₄N₅O₂₁P
• 分子量: 817.6
• InChiKey: MVECABYWTTTXFD-WXIHFFHXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -8.2
• 重原子数：
  55
• 可旋转键数：
  14
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  403
• 氢给体数：
  13
• 氢受体数：
  25

文献信息

• NUCLEOTIDE ANALOGS AND PROCESS FOR MAKING SAME ENZYME
  申请人：MARINO JOHN P.

  公开号：US20140170711A1

  公开（公告）日：2014-06-19

  A process for making a nucleotide analog includes combining a first substrate that includes a linker and a base with a second substrate to form a substrate composition. An enzyme contacts the substrate composition and catalyzes formation of the nucleotide analog from the first substrate and the second substrate. Additionally, a composition includes the first substrate, second substrate, the enzyme, the nucleotide analog, and optional additives.
• US9534243B2
  申请人：——

  公开号：US9534243B2

  公开（公告）日：2017-01-03