2-(3-Aminopropylamino)ethylsulfanylphosphonic acid;1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: 2-(3-Aminopropylamino)ethylsulfanylphosphonic acid;1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea
• 英文别名: 2-(3-aminopropylamino)ethylsulfanylphosphonic acid;1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea
• 化学式: C14H31ClN5O5PS
• 分子量: 447.9
• InChiKey: LPMCJHNZSZDQNV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.0
• 重原子数：
  27
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  183
• 氢给体数：
  5
• 氢受体数：
  9

文献信息

• [EN] BIOCOMPATIBLE POLYMER COMPOSITIONS FOR TISSUE VOID FILLING<br/>[FR] COMPOSITIONS POLYMÈRES BIOCOMPATIBLES POUR REMPLISSAGE DE VIDE TISSULAIRE
  申请人：UNIV RUTGERS

  公开号：WO2014116716A1

  公开（公告）日：2014-07-31

  Biodegradable, bioabsorhahie cross-linked polymer tissue scaffolds for filling a void in human or animal soft tissue, such as a surgical or other wound, are disclosed. Drugs incorporated into the polymer backbone and/or loaded into the matrix are released directly to the target site. Additional non-toxic chemical constituents can be used to tune the hydrophilio hydrophobic and other physical properties of the cross-linked polymer tissue scaffolds, and incorporating brominated or iodinated constituents provides radio-opacity. The radio-opaque cross-linked polymer tissue scaffolds can assist in the targeting of radiation therapy.