4-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 4-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide
• 英文别名: 4-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide
• 化学式: C₂₂H₂₆ClN₇O₂S
• 分子量: 488.0
• InChiKey: OYGBCUGACYIPMY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  33
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  149
• 氢给体数：
  3
• 氢受体数：
  9

文献信息

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  公开（公告）日：2008-08-06
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  申请人：Board of Regents of the University of Texas System

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  公开（公告）日：2009-11-18
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  公开（公告）日：2010-10-06
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  公开（公告）日：2020-02-05