申请人：Whittingham Guy William
公开号：US20050065032A1
公开（公告）日：2005-03-24
Fungicidal compounds of the general formula (I): wherein X and Y are independently H, halo, C
1-8
alkyl, C
3-6
cycloalkyl, C
2-8
alkenyl, C
2-8
alkynyl, C
1-8
alkoxy, C
1-8
alkylthio, nitro, amino, mono- or di-(C
1-6
)alkylamino, mono- or di-(C
2-6
)alkenylamino, mono- or di-(C
2-6
)alkynylamino, formylamino, C
1-4
alkyl(formyl)amino, C
1-4
alkylcarbonylamino, C
1-4
alkyl(C
1-4
alkylcarbonyl)amino, cyano, formyl, C
1-4
alkylcarbonyl, C
1-4
alkoxycarbonyl, aminocarbonyl, mono- or di-(C
1-4
)alkylaminocarbonyl, carboxy, C
1-4
alkylcarbonyloxy, aryl(C
1-4
)alkylcarbonyloxy, C
1-4
alkylsulphinyl, C
1-4
alkylsulphonyl, C
1-4
alkylsulphonyloxy, aryl, heteroaryl, aryloxy, arylthio, heteroaryloxy or heteroarylthio wherein any of the foregoing alkyl, cycloalkyl, alkenyl, alkynyl, aryl, heteroaryl, groups or moieties are optionally substituted; R
1
is phenyl, cyano, C
1-4
alkyl, C
2-4
alkenyl or C
2-4
alkynyl in which the alkyl, alkenyl and alkynyl groups are optionally substituted on their terminal carbon atom with one, two or thre halogen atoms, with a cyano group, with a C
1-4
alkylcarbonyl group, with a C
1-4
alkoxycarbonyl group or with a hydroxy group, or R
1
is alkoxyalkyl, alkylthioalkyl, alkylsulphinylalkyl or alkylsulphonylalkyl in which the total number of carbon atoms is 2 or 3; R
2
is H, C
1-4
alkyl, C
1-4
alkoxymethyl or benzyloxymethyl in which the phenyl ring of the benzyl moiety is optionally substituted with C
1-4
alkoxy; R
3
and R
4
are independently H, C
1-3
alkyl, C
2-3
alkenyl or C
2-3
alkynyl provided that both are not H and that when both are other than H their combined total of carbon atoms does not exceed 4, or R
3
and R
4
join with the carbon atom to which they are attached to form a 3 or 4 membered carbocyclic ring optionally containing one O, S or N atom and optionally substituted with halo or C
1-4
alkyl; and R
5
is halo, C
1-4
alkyl or C
3-4
cycloalkyl in which the alkyl or cycloalkyl group is optionally substituted with halo, hydroxy, C
1-6
alkoxy, C
1-6
alkylthio, cyano, C
1-4
alkylcarbonyloxy, aminocarbonyloxy, mono- or di(C
1-4
)alkylaminocarbonyloxy, or tri(C
1-4
)alkylsilyloxy. The compounds and compositions containing them are especially useful for combating fungal infections of plants.
通式（I）的杀真菌化合物：其中X和Y独立地为H、卤素、C1-8烷基、C3-6环烷基、C2-8烯基、C2-8炔基、C1-8烷氧基、C1-8烷基硫基、硝基、氨基、单取代或双取代（C1-6）烷基氨基、单取代或双取代（C2-6）烯基氨基、单取代或双取代（C2-6）炔基氨基、甲酰氨基、C1-4烷基（甲酰）氨基、C1-4烷基羰基氨基、C1-4烷基（C1-4烷基羰基）氨基、氰基、甲酰基、C1-4烷基羰基、C1-4烷氧基羰基、氨基羰基、单取代或双取代（C1-4）烷基氨基羰基、羧基、C1-4烷基羰氧基、芳基（C1-4）烷基羰氧基、C1-4烷基亚磺酰基、C1-4烷基磺酰基、C1-4烷基磺酰氧基、芳基、杂芳基、芳氧基、芳硫基、杂芳氧基或杂芳硫基，其中上述任何烷基、环烷基、烯基、炔基、芳基、杂芳基、基团或官能团均可选择性地被取代；R1为苯基、氰基、C1-4烷基、C2-4烯基或C2-4炔基，其中烷基、烯基和炔基基团在其末端碳原子上可选择性地用一个、两个或三个卤素原子、一个氰基、一个C1-4烷基羰基、一个C1-4烷氧基羰基或一个羟基取代，或者R1为烷氧烷基、烷硫烷基、烷亚磺酰烷基或烷磺酰烷基，其中总碳原子数为2或3；R2为H、C1-4烷基、C1-4烷氧甲基或苄氧甲基，其中苄基官能团的苯环可选择性地用C1-4烷氧基取代；R3和R4独立地为H、C1-3烷基、C2-3烯基或C2-3炔基，前提是两者不都为H，且当两者都不为H时，它们的总碳原子数不超过4，或者R3和R4与它们附着的碳原子结合形成一个3或4元环烷基，其中可选择性地含有一个O、S或N原子并可选择性地用卤素或C1-4烷基取代；R5为卤素、C1-4烷基或C3-4环烷基，其中烷基或环烷基基团可选择性地用卤素、羟基、C1-6烷氧基、C1-6烷基硫基、氰基、C1-4烷基羰氧基、氨基羰氧基、单取代或双取代（C1-4）烷基氨基羰氧基或三取代（C1-4）硅烷氧基取代。这些化合物和含有它们的组合物特别适用于防治植物真菌感染。
