undecyl-urea | 4128-38-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: undecyl-urea
• 英文别名: n-Undecyl-harnstoff；Undecyl-harnstoff；Undecylurea
• CAS: 4128-38-5
• 化学式: C₁₂H₂₆N₂O
• 分子量: 214.351
• InChiKey: HOAIHZDQHXHYOO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  15
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  55.1
• 氢给体数：
  2
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  potassium cyanate 、 alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 、 水 作用下， 生成 undecyl-urea
  参考文献：
  名称：

  Jeffreys, American Chemical Journal, 1899, vol. 22, p. 41

  摘要：

  DOI：

文献信息

• [EN] TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF<br/>[FR] COMPOSÉS MODULATEURS DE TLR2, COMPOSITIONS PHARMACEUTIQUES ET LEURS UTILISATIONS
  申请人：AXIAL THERAPEUTICS INC

  公开号：WO2021242923A1

  公开（公告）日：2021-12-02

  The present disclosure relates to compounds which modulate the activity of Toll-like receptor (TLR) proteins, including agonists or activators, partial agonists, and antagonists. Of particular interest of compounds that modulate the activity of TLR2, as well as methods of using such compounds to treat cancer and other disorders associated with a TLR2 pathway.

  本公开涉及调节Toll样受体（TLR）蛋白活性的化合物，包括激动剂或激活剂、部分激动剂和拮抗剂。特别感兴趣的是调节TLR2活性的化合物，以及使用这些化合物治疗与TLR2通路相关的癌症和其他疾病的方法。
• Novel lipopeptides as antibacterial agents
  申请人：——

  公开号：US20040067878A1

  公开（公告）日：2004-04-08

  The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.

  本发明涉及新型脂肽类化合物。该发明还涉及这些化合物的药物组合物以及将这些化合物用作抗菌化合物的方法。该发明还涉及生产这些新型脂肽类化合物的方法以及用于生产这些化合物的中间体。
• [EN] LIPOPEPTIDES AS ANTIBACTERIAL AGENTS<br/>[FR] LIPOPEPTIDES UTILES EN TANT QU'AGENTS ANTIBACTERIENS
  申请人：CUBIST PHARM INC

  公开号：WO2001044274A1

  公开（公告）日：2001-06-21

  The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.

  本发明涉及新型脂肽化合物。本发明还涉及这些化合物的药物组合物和将这些化合物用作抗菌化合物的方法。本发明还涉及制备这些新型脂肽化合物和用于制备这些化合物的中间体的方法。
• Novel Lipopeptides as Antibacterial Agents
  申请人：Hill Jason

  公开号：US20090011977A1

  公开（公告）日：2009-01-08

  The present invention relates to novel lipopeptide compounds. The invention also relates to pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The invention also relates to methods of producing these novel lipopeptide compounds and intermediates used in producing these compounds.

  本发明涉及新型脂肽化合物。本发明还涉及这些化合物的药物组合物以及将这些化合物用作抗菌化合物的方法。本发明还涉及生产这些新型脂肽化合物的方法以及用于生产这些化合物的中间体。
• Process for preparation of metallic bottles
  申请人：TOYO SEIKAN KAISHA LIMITED

  公开号：EP0076634A1

  公开（公告）日：1983-04-13

  Disclosed is a process for the preparation of metallic bottles which comprises lap-bonding circumferential open end portions of upper and lower members, each consisting of a formed cup of a metal, said process being characterized by using at least one thermoplastic resin adhesive having a water absorption of less than 2%, as measured at a temperature of 23°C and a relative humidity of 80%, and an elasticity contribution ratio [R(t)t=1] of from 1 x 10-4 to 5 x 10-1, defined by the following formula: wherein J(t)t=1 represents a creep compliance at a time constant of 1 second when the adhesive is caused to creep at a temperature higher by 30°C than the melting point of the adhesive under a shear stress of 50 to 5,000 dyne/cm2, and J(t)rec,t=1 represents an equilibrium recovery creep compliance when the adhesive is caused to creep under the same conditions as described above and the adhesive is then let to recover, and containing in the main or side chain groups at a concentration of 10 to 1400 milliequivalents per 100 g of the adhesive.

  本发明公开了一种制备金属瓶的工艺，该工艺包括搭接粘接上下构件的圆周开口端部，每个构件都由一个成形的金属杯组成，所述工艺的特点是使用至少一种热塑性树脂粘合剂，该粘合剂在温度为23℃和相对湿度为80%的条件下测量，吸水率小于2%，弹性贡献率[R(t)t=1]为1×10-4至5×10-1，由下式定义： 其中，J(t)t=1 代表时间常数为 1 秒时的蠕变顺应性，即在剪切应力为 50 至 5000 达因/厘米2 的条件下，在比粘合剂熔点高 30℃的温度下使粘合剂发生蠕变；J(t)rec,t=1 代表平衡恢复蠕变顺应性，即在与上述相同的条件下使粘合剂发生蠕变，然后让粘合剂恢复，并且在主链或侧链基团中含有 浓度为每 100 克粘合剂 10 至 1400 毫当量。