bis[4-(trifluoromethoxy)-phenyl](1-{[(4-(4-methyl(1,3-dioxolan-2-yl))phenyl)]methyl}(4-piperidyl))methan-1-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: bis[4-(trifluoromethoxy)-phenyl](1-{[(4-(4-methyl(1,3-dioxolan-2-yl))phenyl)]methyl}(4-piperidyl))methan-1-ol
• 英文别名: [1-[[4-(4-Methyl-1,3-dioxolan-2-yl)phenyl]methyl]piperidin-4-yl]-bis[4-(trifluoromethoxy)phenyl]methanol
• 化学式: C₃₁H₃₁F₆NO₅
• 分子量: 611.581
• InChiKey: IUFHXPUFRMMJRB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  43
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  60.4
• 氢给体数：
  1
• 氢受体数：
  12

反应信息

• 作为产物：
  描述：

  1,2-丙二醇 、 4-({4-[bis(4-(trifluoromethoxy)phenyl)hydroxymethyl]piperidinyl}methyl)benzaldehyde 在 对甲苯磺酸 作用下， 以 甲苯 为溶剂， 反应 16.0h， 生成 bis[4-(trifluoromethoxy)-phenyl](1-{[(4-(4-methyl(1,3-dioxolan-2-yl))phenyl)]methyl}(4-piperidyl))methan-1-ol
  参考文献：
  名称：

  WO2006/65659

  摘要：

  公开号：

文献信息

• INSECTICIDAL BIS(SUBSTITUTED PHENYL)-1-{[4-(SATURATED HETEROCYCLYL-SUBSTITUTED)PHENYLMETHYL]- (4-PIPERIDYL)}METHANE DERIVATIVES
  申请人：Lyga John W.

  公开号：US20090082203A1

  公开（公告）日：2009-03-26

  It has now been found that certain novel bis(substituted phenyl)-1 [4-(saturated heterocyclyl-substituted)phenyl-methyl](4-piperidyl)}methane derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I); where R through R 15 , m, n, s, A, B, D and W are defined herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula (I), and optionally, an effective amount of at least one of a second compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present.

  现在已经发现，某些新型的双（取代苯基）-1 [4-（饱和杂环取代）苯基甲基](4-哌啶基)}甲烷衍生物提供了意想不到的杀虫活性。这些化合物由式（I）表示; 其中R到R15，m，n，s，A，B，D和W在此定义。此外，本文还披露了包含式（I）中至少一种化合物的杀虫有效量和可选地至少一种第二化合物的有效量的组合物，其中至少包含一种杀虫剂兼容载体; 以及控制昆虫的方法，包括将所述组合物应用于昆虫存在或预计存在的地点。
• EP1828127A4
  申请人：——

  公开号：EP1828127A4

  公开（公告）日：2009-04-29
• INSECTICIDAL BIS(SUBSTITUTED PHENYL)-1-äÝ4-(SATURATED HETEROCYCLYL-SUBSTITUTED)PHENYLMETHYL¨-(4-PIPERIDYL)üMETHANE DERIVATIVES
  申请人：BAYER CROPSCIENCE AG

  公开号：EP1828127A2

  公开（公告）日：2007-09-05
• [EN] INSECTICIDAL BIS(SUBSTITUTED PHENYL)-1-{[4-(SATURATED HETEROCYCLYL-SUBSTITUTED)PHENYLMETHYL]-(4-PIPERIDYL)}METHANE DERIVATIVES<br/>[FR] DERIVES DE METHANE BIS(PHENYLE SUBSTITUE)-1-{[4-(HETEROCYCLYLE SATURE SUBSTITUE)PHENYLMETHYLE]-(4-PIPERIDYLE)}
  申请人：FMC CORP

  公开号：WO2006065659A2

  公开（公告）日：2006-06-22

  [EN] It has now been found that certain novel bis(substituted phenyl)-1­ [4-(saturated heterocyclyl-substituted)phenylmethyl](4-piperidyl)}methane derivatives have provided unexpected insecticidal activity. These compounds are represented by formula (I); where R through R¹⁵,^{m, n, s, A, B, D and W are defined herein. In addition, compositions comprising an insecticidally effective amount of at least one compound of formula (I), and optionally, an effective amount of at least one of a second compound, with at least one insecticidally compatible carrier are also disclosed; along with methods of controlling insects comprising applying said compositions to a locus where insects are present or are expected to be present.
  [FR] Il a été découvert que certains nouveaux dérivés de méthane bis(phényle substitué)-[4-(hétérocyclyle saturé substitué)phénylméthyle](4-pipéridyle)} ont fourni une activité insecticide inattendue. Ces composés sont représentés par la formule (I) dans laquelle R à R15, m, n, s, A, B, D et W y sont définies. L'invention concerne, en outre, des compositions comprenant une quantité insecticide efficace d'au moins un composé de formule (I), et éventuellement une quantité efficace d'au moins un second composé, avec au moins un support insecticide compatible, ainsi que des procédés destinés à réguler la présence d'insectes qui consistent à appliquer ces compositions à un lieu dans lequel les insectes sont présents ou probablement présents.}
• WO2006/65659
  申请人：——

  公开号：——

  公开（公告）日：——