tributyl{2-[(tributylsilyl)methyl]prop-2-enyl}silane

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: tributyl{2-[(tributylsilyl)methyl]prop-2-enyl}silane
• 英文别名: Tributyl-[2-(tributylsilylmethyl)prop-2-enyl]silane；tributyl-[2-(tributylsilylmethyl)prop-2-enyl]silane
• 化学式: C₂₈H₆₀Si₂
• 分子量: 452.955
• InChiKey: ZKLHQIXHKJDFKV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.24
• 重原子数：
  30
• 可旋转键数：
  22
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  3-氯-2-氯甲基丙烯 、 三丁基氯硅烷 在 萘 、 lithium 作用下， 以 四氢呋喃 为溶剂， 以56%的产率得到tributyl{2-[(tributylsilyl)methyl]prop-2-enyl}silane
  参考文献：
  名称：

  Sulfur dioxide mediated one-pot, four-component synthesis of polyfunctional sulfones and sulfonamides, including medium-ring cyclic derivatives

  摘要：

  In previous papers (Synthesis 2002, 232 and J. Org. Chem. 2004, 69, 6413), we have shown that the hetero-Diels-Alder addition of sulfur dioxide to 1-oxy or 1,3-dioxy- 1,3-dienes generates zwitterions that add to enoxysilanes or allylsilanes giving silyl sulfinates that can be converted in the same pot into polyfunctional sulfones, sulfonamides or sulfonic esters. We are presenting further applications of this method, including the synthesis of new medium-size heterocyclic systems of the type tetrahydro-2H-thiocines and hexahydro-1,2-thiazonine. (c) 2005 Elsevier Ltd, All rights reserved.

  DOI：

  10.1016/j.tet.2005.08.067

文献信息

• Sulfur dioxide mediated one-pot, four-component synthesis of polyfunctional sulfones and sulfonamides, including medium-ring cyclic derivatives
  作者：Laure C. Bouchez、Māris Turks、Srinivas Reddy Dubbaka、Freddy Fonquerne、Cotinica Craita、Sylvain Laclef、Pierre Vogel

  DOI：10.1016/j.tet.2005.08.067

  日期：2005.11

  In previous papers (Synthesis 2002, 232 and J. Org. Chem. 2004, 69, 6413), we have shown that the hetero-Diels-Alder addition of sulfur dioxide to 1-oxy or 1,3-dioxy- 1,3-dienes generates zwitterions that add to enoxysilanes or allylsilanes giving silyl sulfinates that can be converted in the same pot into polyfunctional sulfones, sulfonamides or sulfonic esters. We are presenting further applications of this method, including the synthesis of new medium-size heterocyclic systems of the type tetrahydro-2H-thiocines and hexahydro-1,2-thiazonine. (c) 2005 Elsevier Ltd, All rights reserved.