(1E)-1-[(2-Methyl-1-benzofuran-3-YL)methylidene]-2-phenylhydrazine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 英文名称: (1E)-1-[(2-Methyl-1-benzofuran-3-YL)methylidene]-2-phenylhydrazine
• 英文别名: N-[(E)-(2-methyl-1-benzofuran-3-yl)methylideneamino]aniline
• 化学式: C₁₆H₁₄N₂O
• 分子量: 250.29
• InChiKey: UXDZAUKAFZESJZ-GZTJUZNOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  37.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• SELECTIVE INHIBITORS OF UNDIFFERENTIATED CELLS
  申请人：Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

  公开号：US20150148359A1

  公开（公告）日：2015-05-28

  Uses of a compound of any of Formulas I-VI as a cytotoxic inhibitor of undifferentiated cells are disclosed herein, as well as pharmaceutical compositions comprising a compound of any of Formulas I-VI, and methods for identifying a lead candidate for inhibiting undifferentiated cells. Further disclosed are uses of an SCD-1 inhibitor as a cytotoxic inhibitor of undifferentiated cells.
• US9456998B2
  申请人：——

  公开号：US9456998B2

  公开（公告）日：2016-10-04