tert-butyl N-[(E)-1-(1-benzofuran-2-yl)ethylideneamino]carbamate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 英文名称: tert-butyl N-[(E)-1-(1-benzofuran-2-yl)ethylideneamino]carbamate
• 化学式: C₁₅H₁₈N₂O₃
• 分子量: 274.31
• InChiKey: SUTGRMQIEXRYPD-MHWRWJLKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  63.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Method and composition for the treatment of pain
  申请人：——

  公开号：US20030153571A1

  公开（公告）日：2003-08-14

  A method for the treatment of pain is disclosed comprising administration of a pain-ameliorating effective amount of any compound according to structural diagram I; 1 wherein R 1 , A and D are as defined in the specification. Also disclosed are pharmaceutical compositions comprising a pain-ameliorating effective amount of a compound in accord with structural diagram I.

  本发明揭示了一种治疗疼痛的方法，包括给予任何符合结构式I的化合物的缓解疼痛有效剂量，其中R1，A和D如规范中所定义。此外，还揭示了包含符合结构式I的化合物的缓解疼痛有效剂量的药物组合物。
• METHOD AND COMPOSITION FOR THE TREATMENT OF PAIN
  申请人：AstraZeneca AB

  公开号：EP1244453A1

  公开（公告）日：2002-10-02
• [EN] METHOD AND COMPOSITION FOR THE TREATMENT OF PAIN<br/>[FR] METHODE ET COMPOSITION POUR TRAITER LA DOULEUR
  申请人：ASTRAZENECA AB

  公开号：WO2001047524A1

  公开（公告）日：2001-07-05

  A method for the treatment of pain is disclosed comprising administration of a pain-ameliorating effective amount of any compound according to structural diagram (I); wherein R1, A and D are as defined in the specification. Also disclosed are pharmaceutical compositions comprising a pain-ameliorating effective amount of a compound in accord with structural diagram (I).