4-[4-[2-(4-methylpyridin-2-yl)oxyethyl]piperazin-1-yl]-1H-indole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 4-[4-[2-(4-methylpyridin-2-yl)oxyethyl]piperazin-1-yl]-1H-indole
• 化学式: C₂₀H₂₄N₄O
• 分子量: 336.4
• InChiKey: SULPGVDCLNALLM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  44.4
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Novel indole derivatives
  申请人：Rottländer Mario

  公开号：US20060258678A1

  公开（公告）日：2006-11-16

  A heteroaryl derivative having the formula (I). The compounds of the invention are considered useful for the treatment of affective disorders such as general anxiety disorder, panic disorder, obsessive compulsive disorder, depression, social phobia and eating disorders, and neurological disorders such as psychosis.

  具有公式（I）的杂环芳基衍生物。该发明化合物被认为对治疗情感障碍如普通焦虑症、惊恐障碍、强迫症、抑郁症、社交恐惧症和进食障碍以及神经系统疾病如精神病具有用处。
• NOVEL INDOLE DERIVATIVES
  申请人：H. Lundbeck A/S

  公开号：EP1399434A1

  公开（公告）日：2004-03-24
• US7342015B2
  申请人：——

  公开号：US7342015B2

  公开（公告）日：2008-03-11
• [EN] NOVEL INDOLE DERIVATIVES<br/>[FR] NOUVEAUX DERIVES INDOLIQUES
  申请人：LUNDBECK & CO AS H

  公开号：WO2003002552A1

  公开（公告）日：2003-01-09

  A heteroaryl derivative having the formula (I). The compounds of the invention are considered useful for the treatment of affective disorders such as general anxiety disorder, panic disorder, obsessive compulsive disorder, depression, social phobia and eating disorders, and neurological disorders such as psychosis.