2-[2-[4-(2,3-Dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethoxy]pyridine-4-carbonitrile

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 2-[2-[4-(2,3-Dihydro-1,4-benzodioxin-5-yl)piperazin-1-yl]ethoxy]pyridine-4-carbonitrile
• 化学式: C₂₀H₂₂N₄O₃
• 分子量: 366.4
• InChiKey: OEPMXIGTJKYHRH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  70.8
• 氢给体数：
  0
• 氢受体数：
  7

文献信息

• Novel heteroaryl derivatives, their preparation and use
  申请人：——

  公开号：US20040248883A1

  公开（公告）日：2004-12-09

  A heteroaryl derivative having the formula (I). The compounds of the invention are considered useful for the treatment of affective disorders such as general anxiety disorder, panic disorder, obsessive compulsive disorder, depression, social phobia and eating disorders, and neurological disorders such as psychosis. 1

  具有公式（I）的杂环芳基衍生物。本发明的化合物被认为对治疗情感障碍如广泛性焦虑障碍、恐慌障碍、强迫症、抑郁症、社交恐惧症和进食障碍，以及神经系统障碍如精神病具有有用作用。
• NOVEL HETEROARYL DERIVATIVES, THEIR PREPARATION AND USE
  申请人：H. LUNDBECK A/S

  公开号：EP1399438B1

  公开（公告）日：2005-12-07
• US7393845B2
  申请人：——

  公开号：US7393845B2

  公开（公告）日：2008-07-01
• [EN] NOVEL HETEROARYL DERIVATIVES, THEIR PREPARATION AND USE<br/>[FR] NOUVEAUX DERIVES HETEROARYLE, PREPARATION ET UTILISATION DE CEUX-CI
  申请人：LUNDBECK & CO AS H

  公开号：WO2003002556A1

  公开（公告）日：2003-01-09

  A heteroaryl derivative having the formula (I). The compounds of the invention are considered useful for the treatment of affec tive disorders such as general anxiety disorder, panic disorder, obsessive compulsive disorder, depression, social phobia and eating disorders, and neurological disorders such as psychosis.