(2S)-2-hydroxy-3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: (2S)-2-hydroxy-3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid
• 化学式: C₉H₂₀N₂O₅S
• 分子量: 268.33
• InChiKey: GIZQLVPDAOBAFN-VIFPVBQESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.6
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  110
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• PH-MODULATING BIODEGRADABLE POLYMER AND POLY(GLYCEROL SEBACATE)-AUGMENTED CELL CULTURE MEDIA
  申请人：The Secant Group, LLC

  公开号：EP3740529A1

  公开（公告）日：2020-11-25
• [EN] METHODS AND SYSTEMS FOR PRINTING BIOLOGICAL MATERIAL<br/>[FR] PROCÉDÉS ET SYSTÈMES D'IMPRESSION D'UN MATÉRIAU BIOLOGIQUE
  申请人：PRELLIS BIOLOGICS INC

  公开号：WO2018165613A1

  公开（公告）日：2018-09-13

  The present disclosure provides methods and systems for printing a three-dimensional (3D) material. In some examples, a method for printing a 3D biological material comprises providing a media chamber comprising a medium comprising (i) a plurality of cells and (ii) one or more polymer precursors. Next, at least one energy beam may be directed to the medium in the media chamber along at least one energy beam path that is patterned into a 3D projection wherein the x, y, and z dimensions may be simultaneously accessed in accordance with computer instructions for printing the 3D biological material in computer memory, to form at least a portion of the 3D biological material comprising (i) at least a subset of the plurality of cells, and (ii) a polymer formed from the one or more polymer precursors.
• [EN] pH-MODULATING BIODEGRADABLE POLYMER AND POLY(GLYCEROL SEBACATE)-AUGMENTED CELL CULTURE MEDIA<br/>[FR] POLYMÈRE BIODÉGRADABLE MODULANT LE PH ET SUPPORT DE CULTURE CELLULAIRE ENRICHI EN POLY (SÉBACATE DE GLYCÉROL)
  申请人：SECANT GROUP LLC

  公开号：WO2019143834A1

  公开（公告）日：2019-07-25

  A pH-modulating poly(glycerol sebacate) composition includes poly(glycerol sebacate) and at least one pH-modulating agent associated with the poly(glycerol sebacate). A process of making a pH-modulating poly(glycerol sebacate) composition includes forming a poly(glycerol sebacate) by a water-mediated reaction from glycerol and sebacic acid and associating at least one pH-modulating agent with the poly(glycerol sebacate). A process of modulating a pH of a buffered aqueous solution includes placing a pH-modulating poly(glycerol sebacate) composition in a buffered aqueous solution. The pH-modulating agent is released into the buffered aqueous solution during degradation of the poly(glycerol sebacate) to reduce a decrease in pH of the buffered aqueous solution caused by degradation of the poly(glycerol sebacate).