尿囊素生物素盐 | 4492-73-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 生物素及其衍生物
• 中文名称: 尿囊素生物素盐
• 中文别名: 尿囊素生物素
• 英文名称: Allantoin biotin
• 英文别名: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid;(2,5-dioxoimidazolidin-4-yl)urea
• CAS: 4492-73-3
• 化学式: C14H22N6O6S
• 分子量: 402.43
• InChiKey: DCWBLFMYZJBXPI-UFLZEWODSA-N

物化性质

• LogP：
  0.115 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.38
• 重原子数：
  27
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  217
• 氢给体数：
  7
• 氢受体数：
  7

文献信息

• EP2337544A2
  申请人：——

  公开号：EP2337544A2

  公开（公告）日：2011-06-29
• SKIN PENETRATING DELIVERY SYSTEM BASED ON POSITIVELY CHARGED SUGAR EMULSIFIERS
  申请人：Evonik Operations GmbH

  公开号：EP3334405B1

  公开（公告）日：2021-09-29
• Pharmaceutical and cosmeceutical wash-off mousse shampoo compositions, processes for preparing the same and uses thereof
  申请人：Arkin Moshe

  公开号：US20060057075A1

  公开（公告）日：2006-03-16

  A pharmaceutical or cosmeceutical mousse shampoo composition formulated for application to hirsute areas, such as the human scalp, and containing an active pharmaceutical ingredient as well as a cleansing agent is disclosed. Methods of treatment using the same and processes of preparing the same are also disclosed.
• USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE
  申请人：Yu Betty

  公开号：US20090068255A1

  公开（公告）日：2009-03-12

  The application of matrix metalloproteinase (MMP) inhibitors to the skin inhibits the degradation of proteins found in the skin including collagen, elastin, and other basement membrane and extracellular matrix protein. MMP inhibitors may be used in both cosmetic compositions and pharmaceutical compositions for application to skin. MMP inhibitors are formulated with a cosmetically suitable vehicle or pharmaceutically acceptable excipient for application to the skin as creams, lotions, ointments, solutions, face masks, etc. As cosmetics, the inventive MMP inhibitor compositions are applied to the skin to prevent or reduce the appearance of wrinkles, pigmentation changes, loss of elasticity, or other effects associated with aging or sun damage. As pharmaceuticals, the inventive MMP inhibitor compositions may also be applied to the skin to treat or prevent a skin disease (e.g., proliferative disease, inflammatory disease).
• Pharmaceutical and Cosmeceutical Wash-Off Mousse Shampoo Compositions, Processes for Preparing the Same and Uses Thereof
  申请人：Arkin Moshe

  公开号：US20110008267A1

  公开（公告）日：2011-01-13

  A method for treating a disease or disorder of the skin or scalp of a mammal while simultaneously cleansing the skin or scalp is disclosed. The method includes administering to the skin or scalp a mousse formed from a composition that includes a therapeutically or cosmeceutically effective amount of at least one active pharmaceutical ingredient, 10% to 50% by weight of a cleansing agent selected from the group consisting of anionic surfactants, nonionic surfactants and combinations thereof, a pharmaceutically acceptable mousse-forming carrier that includes a propellant, the propellant being 3% to 50% by weight of the composition, and water being about 40% to about 90% by weight of the composition, waiting a period of time; and rinsing said skin or scalp with water to remove the mousse.