4-(4-ethyl-piperazin-1-yl)-butylamine | 4486-93-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 4-(4-ethyl-piperazin-1-yl)-butylamine
• 英文别名: 4-(4-Ethylpiperazin-1-yl)butan-1-amine
• CAS: 4486-93-5
• 化学式: C₁₀H₂₃N₃
• 分子量: 185.313
• InChiKey: PZNAFVVVYJUKGS-UHFFFAOYSA-N

物化性质

• 沸点：
  136-139 °C(Press: 15 Torr)
• 密度：
  0.924±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  32.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• BICYCLIC HETEROARYL DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE
  申请人：Jung Seung Hyun

  公开号：US20120302567A1

  公开（公告）日：2012-11-29

  The present invention relates to a novel bicyclic heteroaryl derivative, a pharmaceutically acceptable salt thereof, a hydrate thereof, and a solvate thereof having an improved inhibitory activity for protein kinases, and a pharmaceutical composition for preventing or treating an abnormal cell growth disorder comprising same as an active ingredient.

  本发明涉及一种新颖的双环杂环芳基衍生物，其药用盐，水合物和溶剂合物，具有改进的蛋白激酶抑制活性，并且包括作为活性成分的药物组合物，用于预防或治疗异常细胞生长紊乱。
• OPTICAL RECORDING MEDIUM AND COMPOUND USED FOR THE SAME
  申请人：SHIOZAKI Hiroyoshi

  公开号：US20090306376A1

  公开（公告）日：2009-12-10

  A compound comprising a ring structure including a ring composed of four carbon atoms and two nitrogen atoms and a substituted or unsubstituted amino group bonded to the ring structure.

  一种化合物，包括一个环结构，其中包括由四个碳原子和两个氮原子组成的环，以及与环结构相结合的取代或未取代的氨基团。
• [EN] BRIDGED SPIRO [2.4] HEPTANE DERIVATIVES AS ALX RECEPTOR AND/OR FPRL2 AGONISTS<br/>[FR] DÉRIVÉS DE SPIRO[2.4]HEPTANE PONTÉS UTILES EN TANT QU'AGONISTES DU RÉCEPTEUR DE ALX ET/OU DU RÉCEPTEUR FPRL2
  申请人：ACTELION PHARMACEUTICALS LTD

  公开号：WO2010134014A1

  公开（公告）日：2010-11-25

  The present invention relates to bridged spiro[2.4]heptane derivatives of formula (I), wherein W, Y, Z, R1 and R2 are as defined in the description, their preparation and their use as pharmaceutically active compounds as ALX receptor and/or FPRL2 agonists for the treatment of inflammatory and obstructive airways diseases.

  本发明涉及桥式螺[2.4]庚烷衍生物的化学式(I)，其中W、Y、Z、R1和R2如描述中所定义，它们的制备及其作为药用活性化合物的ALX受体和/或FPRL2激动剂在治疗炎症性和梗阻性气道疾病中的用途。
• BRIDGED SPIRO [2.4] HEPTANE DERIVATIVES AS ALX RECEPTOR AND/OR FPRL2 AGONISTS
  申请人：Bur Daniel

  公开号：US20120115841A1

  公开（公告）日：2012-05-10

  The present invention relates to bridged spiro[2.4]heptane derivatives of formula (I), wherein W, Y, Z, R 1 and R 2 are as defined in the description, their preparation and their use as pharmaceutically active compounds as ALX receptor and/or FPRL2 agonists for the treatment of inflammatory and obstructive airways diseases.

  本发明涉及桥联螺[2.4]庚烷衍生物，其化学式为（I），其中W、Y、Z、R1和R2如描述中所定义，其制备以及作为药物活性化合物的ALX受体和/或FPRL2激动剂用于治疗炎症和阻塞性呼吸道疾病。
• OPTICAL RECORDING MEDIUM AND COMPOUND USED IN THE OPTICAL RECORDING MEDIUM
  申请人：Mitsui Chemicals, Inc.

  公开号：EP1672626A1

  公开（公告）日：2006-06-21

  There are provided an optical recording medium which enables recording and playback with high quality using laser of 300 nm to 900 nm and a novel compound. An optical recording medium wherein the percentage change (|[a2 - a1]/a1| × 100) of the recording layer thickness (a2) at the recorded site of recording layer (A) after recorded with laser light compared with the recording layer thickness (a1) at unrecorded site of said recording layer (A) is less than 25% and the amount of change (|a2 - a1|) of the recording layer thickness (a2) at recorded site of said recording layer (A) after recorded with laser light compared with the recording layer thickness (a1) at unrecorded site of said recording layer (A) is controlled to be less than 15 nm. A compound comprising a six-membered ring structure composed of four carbon atoms and two nitrogen atoms and a substituted or unsubstituted amino group bonded.

  本发明提供了一种光学记录介质，利用波长为 300 纳米至 900 纳米的激光和一种新型化合物可实现高质量的记录和重放。 一种光学记录介质，其中用激光记录后，记录层（A）的记录部位的记录层厚度（a2）与未记录部位的记录层厚度（a1）相比的变化百分比（|[a2-a1]/a1| ×100）小于 25%，且所述记录层（A）的记录部位的记录层厚度（a2）与未记录部位的记录层厚度（a1）相比的变化量（|a2-a1|）小于 25%。a1|）的变化量控制在 15 nm 以下。 一种由四个碳原子和两个氮原子以及一个取代或未取代的氨基键合而成的六元环结构的化合物。