1-苯并呋喃-4-硫醇 | 173306-95-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 中文名称: 1-苯并呋喃-4-硫醇
• 英文名称: 1-Benzofuran-4-thiol
• CAS: 173306-95-1
• 化学式: C₈H₆OS
• 分子量: 150.2
• InChiKey: FIGIMNVKSZXLEK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  14.1
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] THERAPEUTIC PROSTAGLANDIN COMPOUNDS USED AS OCULAR HYPOTENSIVE AGENTS<br/>[FR] COMPOSÉS PROSTAGLANDINES THÉRAPEUTIQUES UTILISÉS EN TANT QU'AGENTS HYPOTENSIFS OCULAIRES
  申请人：ALLERGAN INC

  公开号：WO2009142967A1

  公开（公告）日：2009-11-26

  Compounds comprising or a pharmaceutically acceptable salt or a prodrug thereof are disclosed, wherein a dashed line represents the presence or absence of a bond; and, wherein Y, A, R, D, and n are as described. Methods, compositions, and medicaments related thereto are also disclosed.

  披露了包含或其药用可接受盐或前药的化合物，其中虚线代表键的存在或不存在；以及其中Y、A、R、D和n如所述。还披露了相关的方法、组合物和药物。
• [EN] PHARMACEUTICAL COMPOSITIONS COMPRISING BENZOFURANYL SUBSTITUTED 3-CYANOQUINOLINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF SOLID TUMOURS<br/>[FR] COMPOSITIONS PHARMACEUTIQUES CONTENANT DES DERIVES DE 3-CYANOQUINOLINE A SUBSTITUTION BENZOFURANYLE ET LEUR UTILISATION DANS LE TRAITEMENT DE TUMEURS SOLIDES
  申请人：ASTRAZENECA AB

  公开号：WO2003047585A1

  公开（公告）日：2003-06-12

  The invention concerns the use of a quinoline derivative of the Formula I, wherein each of Z, m, R1, n and R3 have any of the meanings defined hereinbefore in the description, in the manufacture of a medicament for use as an anti-proliferative agent in the containment and/or treatment of solid tumour disease.
• [EN] QUINOLINE DERIVATIVES<br/>[FR] DERIVES DE LA QUINOLINE
  申请人：ASTRAZENECA AB

  公开号：WO2003047584A1

  公开（公告）日：2003-06-12

  The invention concerns quinoline derivatives of Formula (I) wherein each of Z, m, R1, n and R3 have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an anti-invasive agent in the containment and/or treatment of solid tumour disease.