N-[2-[3-[2-[3-[(2R)-2-methylpiperazin-1-yl]pyrazin-2-yl]oxyethoxy]pyridin-2-yl]oxyethyl]-N-propan-2-ylpropan-2-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: N-[2-[3-[2-[3-[(2R)-2-methylpiperazin-1-yl]pyrazin-2-yl]oxyethoxy]pyridin-2-yl]oxyethyl]-N-propan-2-ylpropan-2-amine
• 化学式: C₂₄H₃₈N₆O₃
• 分子量: 458.6
• InChiKey: WXPASJCNNRZVFW-HXUWFJFHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  33
• 可旋转键数：
  12
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  84.9
• 氢给体数：
  1
• 氢受体数：
  9

文献信息

• Novel compounds, their use and preparation
  申请人：——

  公开号：US20040029888A1

  公开（公告）日：2004-02-12

  The invention relates to compounds of the general Formula (I): 1 The compounds may be prepared by per se conventional methods and can be used for treating a human or animal subject suffering from a serotonin-related disorder. The invention also relates to such use as well as to pharmaceutical compositions comprising a compound of Formula (I).

  本发明涉及通式（I）的化合物：1这些化合物可以通过常规方法制备，可用于治疗患有血清素相关疾病的人类或动物受试者。本发明还涉及这种用途以及包含通式（I）化合物的制药组合物。
• NOVEL COMPOUNDS, THEIR USE AND PREPARATION
  申请人：Biovitrum AB

  公开号：EP1513831A1

  公开（公告）日：2005-03-16
• US7226925B2
  申请人：——

  公开号：US7226925B2

  公开（公告）日：2007-06-05
• [EN] NOVEL COMPOUNDS, THEIR USE AND PREPARATION<br/>[FR] NOUVEAUX COMPOSES, LEUR UTILISATION ET LEUR PREPARATION
  申请人：BIOVITRUM AB

  公开号：WO2004000830A1

  公开（公告）日：2003-12-31

  The invention relates to compounds of the general Formula (I). The compounds may be prepared by per se conventional methods and can be used for treating a human or animal subject suffering from a serotonin-related disorder. The invention also relates to such use as well as to pharmaceutical compositions comprising a compound of Formula (I).