2-(4-异氰酸-1-哌嗪基)乙醇 | 151291-43-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 中文名称: 2-(4-异氰酸-1-哌嗪基)乙醇
• 英文名称: 2-(4-Isocyanatopiperazin-1-yl)ethan-1-ol
• 英文别名: 2-(4-isocyanatopiperazin-1-yl)ethanol
• CAS: 151291-43-9
• 化学式: C₇H₁₃N₃O₂
• 分子量: 171.2
• InChiKey: XELSYQUBOFNRAK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  56.1
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
  申请人：GRIFFIOEN Gerard

  公开号：US20090054410A1

  公开（公告）日：2009-02-26

  This invention provides specifically substituted 1,2,4-thiadiazole derivatives for use in the treatment of an α-synucleopathy such as Parkinson's disease, diffuse Lewy body disease, traumatic brain injury, amyotrophic lateral sclerosis, Niemann-Pick disease, Hallervorden-Spatz syndrome, Down syndrome, neuroaxonal dystrophy, multiple system atrophy and Alzheimer's disease. This invention also provides various methods for producing such substituted 1,2,4-thiadiazole derivatives.
• US8541406B2
  申请人：——

  公开号：US8541406B2

  公开（公告）日：2013-09-24