Di-n-butyl-Zinn-chlorid-acetat | 4434-28-0

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机过渡后金属化合物
• 英文名称: Di-n-butyl-Zinn-chlorid-acetat
• 英文别名: Dibutyl(chloro)stannanylium;acetate；dibutyl(chloro)stannanylium;acetate
• CAS: 4434-28-0
• 化学式: C₁₀H₂₁ClO₂Sn
• 分子量: 327.439
• InChiKey: CTESAYWIBGYWGR-UHFFFAOYSA-L

物化性质

• 熔点：
  63-65 °C
• 沸点：
  279.5±23.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.57
• 重原子数：
  14.0
• 可旋转键数：
  6.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  40.13
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  Di-n-butyl-Zinn-chlorid-acetat 、 氯乙酸 以93%的产率得到
  参考文献：
  名称：

  HONNICK W. D.; ZUCKERMAN J. J., J. ORGANOMETAL. CHEM., 1979, 178, NO 1, 133-155,

  摘要：

  DOI：
• 作为产物：
  描述：

  二丁基二氯化锡 、 溶剂黄146 在 三乙胺 作用下， 以 甲苯 为溶剂， 反应 3.0h， 以88%的产率得到Di-n-butyl-Zinn-chlorid-acetat
  参考文献：
  名称：

  Synthesis, characterisation and antimicrobial studies of organotin(IV) complexes with 1,10-phenanthroline derivatives

  摘要：

  The synthesis of several diorganotin(IV) dicarboxylate compounds, including acetates and nicotinates as well as diorganotin(IV) dichloride complexes of the ligands phen, dione and dppz were undertaken. Several difficulties in either the syntheses or complexation reactions with the organic ligands were encountered. The diorganotin(IV) dichloride complexes of the ligands (R2SnCl2 center dot L where R = Me, n-Bu or Ph and L = phen, dione or dppz) were tested against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. The dibutyltin(IV) derivatives exhibited the broadest range of activity in comparison to the dimethyltin(IV) or diphenyltin(IV) derivatives. The addition of the nicotinate group did not promote activity against any of the bacteria. Furthermore, only in the case of Ph2SnCl2 center dot dione was there improved activity compared to the organic ligand itself. (C) 2013 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2013.09.038

文献信息

• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Sn: Org.Verb.1, 1.1.1.5.4.5, page 106 - 108
  作者：

  DOI：——

  日期：——
• Melnichenko, L. S.; Zemlyanskii, N. N.; Kocheshkov, K. A., Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1972, p. 1993 - 1996
  作者：Melnichenko, L. S.、Zemlyanskii, N. N.、Kocheshkov, K. A.

  DOI：——

  日期：——
• Melnichenko, L. S.; Zemlyanskii, N. N.; Kolosova, N. D., Doklady Akademii nauk SSSR, 1971, vol. 196/201, p. 534 - 535
  作者：Melnichenko, L. S.、Zemlyanskii, N. N.、Kolosova, N. D.、Kocheshkov, K. A.

  DOI：——

  日期：——
• Synthesis and spectroscopic studies of thienyl triorganotin(IV) compounds. Crystal structures of [2-(4,4-dimethyl-2-oxazolinyl)-3-thienyl]dimethyltin N,N-dimethyldithiocarbamate and [2-(4,4-dimethyl-2-oxazolinyl)-3-thienyl]diphenyltin chloride
  作者：Kong Mun Lo、S. Selvaratnam、Seik Weng Ng、Chen Wei、V.G. Kumar Das

  DOI：10.1016/0022-328x(92)86003-m

  日期：1992.6

  Two series of stannylated thiophenes of formula (Z-C4H2S)SnR2X (Z = 3-(2-pyridyl) and 2-(4,4-dimethyl-2-oxazolinyl); R = Me, (n)Bu, Ph, p-tolyl and (c)Hex; X = Cl, Br, I, OH, SC(S)NMe2 and 8-quinolinolyl) have been prepared and their structures established by Sn-119m Mossbauer and NMR (C-13 and Sn-119) spectral analyses. A pronounced C,N-chelate bonding mode is inferred for the 3-(2-pyridyl)-2-thienyl ligand in the first series, the tin atoms thus being essentially five-coordinate with trans-C3SnNX trigonal bipyramidal geometries. Crystal structure determinations on two products in the second series, namely [2-(4,4-dimethyl-2-oxazolinyl)-3-thienyl]dimethyltin N,N-dimethyldithiocarbamate (1) and [2-(4,4-dimethyl-2-oxazolinyl)-3-thienyl]diphenyltin chloride (2), confirmed the spectroscopic indications of pentacoordinate trigonal bipyramidal tin environments and revealed that the oxazolinyl nitrogen is the intramolecularly coordinated donor atom in each case and is located in an apical position with respect to the C3Sn trigonal girdle; the Sn-N bond length in 2 (2.580(8); 2.525(7) angstrom) is relatively shorter than in 1 (2.720(3) angstrom). The apical angle for 1 (162.12(7)-degrees) shows the molecule to be more distorted than 2 (168.4(2) and 169.9(2)-degrees).
• Synthesis, characterisation and antimicrobial studies of organotin(IV) complexes with 1,10-phenanthroline derivatives
  作者：Niamh Dolan、John McGinley、John C. Stephens、Kevin Kavanagh、Daniel Hurley、Niall J. Maher

  DOI：10.1016/j.ica.2013.09.038

  日期：2014.1

  The synthesis of several diorganotin(IV) dicarboxylate compounds, including acetates and nicotinates as well as diorganotin(IV) dichloride complexes of the ligands phen, dione and dppz were undertaken. Several difficulties in either the syntheses or complexation reactions with the organic ligands were encountered. The diorganotin(IV) dichloride complexes of the ligands (R2SnCl2 center dot L where R = Me, n-Bu or Ph and L = phen, dione or dppz) were tested against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa. The dibutyltin(IV) derivatives exhibited the broadest range of activity in comparison to the dimethyltin(IV) or diphenyltin(IV) derivatives. The addition of the nicotinate group did not promote activity against any of the bacteria. Furthermore, only in the case of Ph2SnCl2 center dot dione was there improved activity compared to the organic ligand itself. (C) 2013 Elsevier B.V. All rights reserved.