(4-(cyclooct-2-ynyloxy)butyl)triethoxysilane | 1245911-09-4

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: (4-(cyclooct-2-ynyloxy)butyl)triethoxysilane
• 英文别名: (4-(Cyclooct-2-ynyloxy)butyl)triethoxysilane；4-cyclooct-2-yn-1-yloxybutyl(triethoxy)silane
• CAS: 1245911-09-4
• 化学式: C₁₈H₃₄O₄Si
• 分子量: 342.551
• InChiKey: QTTYZFVFHNOGNM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.17
• 重原子数：
  23
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  36.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  8,8-dibromobicyclo[5.1.0]octane 在 铂(0)-1,3-二乙烯-1,1,3,3-四甲基二硅氧烷 silver perchlorate 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 、 氢化铝 作用下， 以 氘代二甲亚砜 、 甲苯 为溶剂， 反应 120.0h， 生成 (4-(cyclooct-2-ynyloxy)butyl)triethoxysilane
  参考文献：
  名称：

  NOVEL SILANE COMPOUNDS HAVING A CYCLIC CARBON CHAIN INCLUDING AN ALKYNE FUNCTION FOR FUNCTIONALISING SOLID SUBSTRATES AND IMMOBILISING BIOLOGICAL MOLECULES ON SAID SUBSTRATES

  摘要：

  该发明涉及一种包括环炔基官能团的硅烷化合物，一种用于官能化固体基质的方法，以及由此生产的固体基质。该发明的硅烷化合物对应于公式X-E-A-Z，其中X是硅基，E是有机间隔基，A是单键或—CONH—，—NHCO—，—OCH2CONH—，—NHCOCH2O—，—O—或—S—基团，Z是至少有8个成员的环炔基或杂环炔基。该发明特别适用于医学领域。

  公开号：

  US20120095203A1

文献信息

• Silane compounds having a cyclic carbon chain including an alkyne function for functionalizing solid substrates and immobilizing biological molecules on said substrates
  申请人：Bernardin Aude

  公开号：US08546598B2

  公开（公告）日：2013-10-01

  The invention relates to a silane compound including a cycloalkyne functionality, to a method for functionalising a solid substrate, and to the solid substrate thus produced. The silane compound of the invention corresponds to the formula X-E-A-Z where X is a silyl group, E is an organic spacer group, A is a single bond or a —CONH—, —NHCO—, —OCH2CONH—, —NHCOCH2O—, —O— or —S— group, and Z is a cycloalkyne or heterocycloalkyne with at least 8 members. The invention is particularly suitable for use in the field of medicine.

  本发明涉及一种包括环烷炔官能团的硅烷化合物，一种用于官能化固体基底的方法，以及由此制得的固体基底。本发明的硅烷化合物对应于公式X-E-A-Z，其中X是硅基团，E是有机间隔基团，A是单键或-CONH-，-NHCO-，-OCH2CONH-，-NHCOCH2O-，-O-或-S-基团，Z是至少有8个成员的环烷炔或杂环烷炔。本发明特别适用于医学领域。
• NOVEL SILANE COMPOUNDS HAVING A CYCLIC CARBON CHAIN INCLUDING AN ALKYNE FUNCTION FOR FUNCTIONALISING SOLID SUBSTRATES AND IMMOBILISING BIOLOGICAL MOLECULES ON SAID SUBSTRATES
  申请人：Bernardin Aude

  公开号：US20120095203A1

  公开（公告）日：2012-04-19

  The invention relates to a silane compound including a cycloalkyne functionality, to a method for functionalising a solid substrate, and to the solid substrate thus produced. The silane compound of the invention corresponds to the formula X-E-A-Z where X is a silyl group, E is an organic spacer group, A is a single bond or a —CONH—, —NHCO—, —OCH 2 CONH—, —NHCOCH 2 O—, —0— or —S— group, and Z is a cycloalkyne or heterocycloalkyne with at least 8 members. The invention is particularly suitable for use in the field of medicine.

  该发明涉及一种包括环炔基官能团的硅烷化合物，一种用于官能化固体基质的方法，以及由此生产的固体基质。该发明的硅烷化合物对应于公式X-E-A-Z，其中X是硅基，E是有机间隔基，A是单键或—CONH—，—NHCO—，—OCH2CONH—，—NHCOCH2O—，—O—或—S—基团，Z是至少有8个成员的环炔基或杂环炔基。该发明特别适用于医学领域。