P-iso-propyl-P-chloro-N,N-bis(trimethylsilyl)aminophosphine | 81072-82-4

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: P-iso-propyl-P-chloro-N,N-bis(trimethylsilyl)aminophosphine
• 英文别名: 2-[[Bis(trimethylsilyl)amino]-chlorophosphanyl]propane
• CAS: 81072-82-4
• 化学式: C₉H₂₅ClNPSi₂
• 分子量: 269.902
• InChiKey: HJBMUOCGIJDFEV-UHFFFAOYSA-N

物化性质

• 沸点：
  246.0±23.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.92
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  P-iso-propyl-P-chloro-N,N-bis(trimethylsilyl)aminophosphine 在 溴 作用下， 以 四氢呋喃 、 甲苯 为溶剂， 反应 1.5h， 生成 C₉H₂₃BrNPSi
  参考文献：
  名称：

  Synthesis and Characterization of Mixed-Substituent P- n -Propyl-N-trimethylsilylphosphoranimines

  摘要：

  One approach to the synthesis of polyphosphazenes is the condensation polymerization of phosphoranimines. In this work, several novel P-n-propyl-N-trimethylsilylphosphoranimines have been synthesized and characterized. Modifications to the literature synthetic routes were required to obtain the precursor phosphines. The N-trimethylsilylphosphoranimines were obtained though oxidation of the phosphine with bromine and then subsequent nucleophilic displacement using lithium phenoxide. These phosphoranimines were stable for long periods of time under dry inert conditions. NMR analyses revealed complex splitting patterns beyond typical coupling due to the stereocenter at phosphorus. We report several approaches to the n-propyl containing phosphines and phosphoranimines.

  DOI：

  10.1080/10426500307867
• 作为产物：
  描述：

  六甲基二硅氮烷 在 正丁基锂 作用下， 以 乙醚 、 正己烷 为溶剂， 生成 P-iso-propyl-P-chloro-N,N-bis(trimethylsilyl)aminophosphine
  参考文献：
  名称：

  Synthesis and Characterization of Mixed-Substituent P- n -Propyl-N-trimethylsilylphosphoranimines

  摘要：

  One approach to the synthesis of polyphosphazenes is the condensation polymerization of phosphoranimines. In this work, several novel P-n-propyl-N-trimethylsilylphosphoranimines have been synthesized and characterized. Modifications to the literature synthetic routes were required to obtain the precursor phosphines. The N-trimethylsilylphosphoranimines were obtained though oxidation of the phosphine with bromine and then subsequent nucleophilic displacement using lithium phenoxide. These phosphoranimines were stable for long periods of time under dry inert conditions. NMR analyses revealed complex splitting patterns beyond typical coupling due to the stereocenter at phosphorus. We report several approaches to the n-propyl containing phosphines and phosphoranimines.

  DOI：

  10.1080/10426500307867

文献信息

• Synthesis and reactivity of P-acetylenic (silylamino)phosphines
  作者：Robert H Neilson、William R Kucera

  DOI：10.1016/s0022-328x(01)01441-3

  日期：2002.3

  compounds, (Me3Si)2NP(CCR)2 (1: R=SiMe3; 2: R=n-Bu; 3: R=CH2OCH3), (Me3Si)2NP(Ph)CCSiMe3 (4), and (Me3Si)2NP(R)CCCH2OCH3 (5: R=i-Pr; 6: R=CH2SiMe3; 7: R=n-Bu) were obtained from the reactions of C-lithiated acetylenes LiCCR with either mono- or dichloro substituted (silylamino)phosphines. Similar reactions involving HCCMgCl gave the parent P-ethynyl derivatives, (Me3Si)2NP(R)CCH (12: R=CH2SiMe3;

  标题化合物（Me 3 Si）2 NP（CCR）2（1：R = SiMe 3 ; 2：R = n -Bu; 3：R = CH 2 OCH 3），（Me 3 Si）2 NP （PH）CCSiMe 3（4），和（ME 3 Si）的2 NP（R）CCCH 2 OCH 3（5：R =我-Pr; 6：R = CH 2森达3 ; 7：R = ñ-Bu）是由C-化的乙炔LiCCR与单或二氯取代的（甲硅烷基氨基）膦反应制得的。涉及HCCMgCl的类似反应得到母体P-乙炔基衍生物，（Me 3 Si）2 NP（R）CCH（12：R ＝ CH 2 SiMe 3；13：R ＝ Ph）。去质子化取代在终端CH组12容易地得到我3硅衍生物，（ME 3 Si）的2 NP（CH 2森达3）CCSiMe 3（14）。7的氧化溴化反应生成对-溴磷酸氨基苯胺3 SiNP（Ñ -Bu）（CCCH 2 OCH 3
• Cavell, Ronald G.; Angelov, Christo M.; Mazzuca, Dean A., Phosphorus, Sulfur and Silicon and the Related Elements, 1996, vol. 109, # 1-4, p. 625 - 628
  作者：Cavell, Ronald G.、Angelov, Christo M.、Mazzuca, Dean A.

  DOI：——

  日期：——