1-Methanesulfonyl-3-methyl-butan-2-one | 85057-89-2

• 分子结构分类: 有机化合物 - 有机硫化合物 - 磺酰类
• 英文名称: 1-Methanesulfonyl-3-methyl-butan-2-one
• 英文别名: 3-Methyl-1-methylsulfonylbutan-2-one
• CAS: 85057-89-2
• 化学式: C₆H₁₂O₃S
• 分子量: 164.225
• InChiKey: OKUHKAOIIUIEBY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  59.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  对甲苯磺酸正丁酯 、 1-Methanesulfonyl-3-methyl-butan-2-one 生成 3-Methyl-1-pentylsulfonyl-2-butanon
  参考文献：
  名称：

  Scholz, Dieter, Liebigs Annalen der Chemie, 1983, # 1, p. 98 - 106

  摘要：

  DOI：

文献信息

• MACROCYCLIC COMPOUNDS FOR INHIBITION OF INHIBITORS OF APOPTOSIS
  申请人：Ensemble Therapeutics Corp.

  公开号：US20140135270A1

  公开（公告）日：2014-05-15

  There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.

  这里公开了调节凋亡抑制剂（IAPs）活性的化合物，包含所述化合物的药物组合物以及使用本发明的化合物治疗增殖性疾病和凋亡失调疾病的方法，例如癌症。
• Hepatitis C Virus Inhibitors
  申请人：Bristol-Myers Squibb Company

  公开号：US20150023913A1

  公开（公告）日：2015-01-22

  The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.

  本公开涉及抗病毒化合物，更具体地涉及能够抑制由丙型肝炎病毒（HCV）编码的NS5A蛋白功能的化合物组合，包括这种组合的组成物，以及抑制NS5A蛋白功能的方法。
• BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS
  申请人：BAYER CROPSCIENCE AKTIENGESELLSCHAFT

  公开号：US20170327487A1

  公开（公告）日：2017-11-16

  The present application relates to novel bicyclic compounds, to compositions comprising these compounds, to their use for controlling animal pests and to processes and intermediates for their preparation.

  本申请涉及新颖的双环化合物，包括这些化合物的组合物，它们用于控制动物害虫的用途，以及用于制备这些化合物的过程和中间体。
• Hepatitis C Inhibitor Dipeptide Analogs
  申请人：BAILEY Murray D.

  公开号：US20090156822A1

  公开（公告）日：2009-06-18

  Compounds of formula (I): wherein R 1 , R 2 , R 3 , R 4 , n and m are as defined herein. The compounds are useful as inhibitors of HCV NS3 protease.

  式(I)的化合物：其中R1、R2、R3、R4、n和m的定义如本文所述。该化合物可用作HCV NS3蛋白酶的抑制剂。
• Combinations of Hepatitis C Virus Inhibitors
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：US20160158200A1

  公开（公告）日：2016-06-09

  The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.

  本公开涉及抗病毒化合物，更具体地涉及能够抑制丙型肝炎病毒（HCV）编码的NS5A蛋白功能的化合物组合，包含这种组合的组合物，以及抑制NS5A蛋白功能的方法。