1-(4-hydroxy-2,5-dimethylphenyl)-6-syringoyl-β-D-glucopyranose | 1415220-21-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 单宁
• 英文名称: 1-(4-hydroxy-2,5-dimethylphenyl)-6-syringoyl-β-D-glucopyranose
• 英文别名: dunnianoside A；[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(4-hydroxy-2,5-dimethylphenoxy)oxan-2-yl]methyl 4-hydroxy-3,5-dimethoxybenzoate
• CAS: 1415220-21-1
• 化学式: C₂₃H₂₈O₁₁
• 分子量: 480.469
• InChiKey: FYJAWROLMJRKTI-OXUVVOBNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  34
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  164
• 氢给体数：
  5
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  1-(4-hydroxy-2,5-dimethylphenyl)-6-syringoyl-β-D-glucopyranose 在 盐酸 、 水 作用下， 反应 10.0h， 生成 葡萄糖
  参考文献：
  名称：

  Antioxidant phenolic glycosides from the roots of Illicium dunnianum

  摘要：

  Eight new phenolic glycosides, dunnianosides A-H (1-8), and nine known phenolic glycosides (9-17), were isolated from the roots of Illicium dunnianum. The structures of these new compounds were elucidated by spectroscopic methods including 1D and 2D NMR, HRESIMS, and chemical methods. Compounds 1-5, 7, and 9 exhibited potent antioxidant activities against Fe2+-cystine-induced rat liver microsomal lipid peroxidation, with IC50 values ranging from 3.8 +/- 0.6 to 23.0 +/- 2.2 mu M. Crown Copyright (c) 2012 Published by Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2012.08.017

文献信息

• Antioxidant phenolic glycosides from the roots of Illicium dunnianum
  作者：Jian Bai、Zhen-Feng Fang、Hui Chen、Shi-Shan Yu、Dan Zhang、Huai-Ling Wei、Shuang-Gang Ma、Yong Li、Jing Qu、Song Xu、Jing-Hong Ren、Fen Zhao、Nan Zhao、Jun-Hong Liu

  DOI：10.1016/j.carres.2012.08.017

  日期：2012.11

  Eight new phenolic glycosides, dunnianosides A-H (1-8), and nine known phenolic glycosides (9-17), were isolated from the roots of Illicium dunnianum. The structures of these new compounds were elucidated by spectroscopic methods including 1D and 2D NMR, HRESIMS, and chemical methods. Compounds 1-5, 7, and 9 exhibited potent antioxidant activities against Fe2+-cystine-induced rat liver microsomal lipid peroxidation, with IC50 values ranging from 3.8 +/- 0.6 to 23.0 +/- 2.2 mu M. Crown Copyright (c) 2012 Published by Elsevier Ltd. All rights reserved.