5,6-diphenyl-3-(pyridin-3-yl)-1,2,4-triazine | 64494-11-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: 5,6-diphenyl-3-(pyridin-3-yl)-1,2,4-triazine
• 英文别名: 5,6-diphenyl-3-pyridin-3-yl-[1,2,4]triazine；3-Pyridyl-(3)-5,6-diphenyl-1,2,4-triazin；5,6-diphenyl-3-pyridin-3-yl-1,2,4-triazine
• CAS: 64494-11-7
• 化学式: C₂₀H₁₄N₄
• 分子量: 310.358
• InChiKey: JPZBMJQHBVWLBN-UHFFFAOYSA-N

物化性质

• 熔点：
  171-173 °C(Solv: acetone (67-64-1); water (7732-18-5))
• 沸点：
  526.5±52.0 °C(Predicted)
• 密度：
  1.202±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  51.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  3-吡啶甲酰肼 、 联苯甲酰 在 ammonium acetate 作用下， 以 溶剂黄146 为溶剂， 反应 5.0h， 以92%的产率得到5,6-diphenyl-3-(pyridin-3-yl)-1,2,4-triazine
  参考文献：
  名称：

  Microwave-initiated living free radical polymerization: optimization of the preparative scale synthesis of Rasta resins

  摘要：

  Microwave heating of high-loading TEMPO-methyl resin with functionalized styrenyl monomers in an ADVANCER (TM) preparative scale microwave synthesizer affords larger resin beads (> 375 mu m) via living free radical polymerization (LFRP). Unlike homogeneous MAOS reactions, the heterogeneous LFRP reaction is not directly scalable and required significant optimization. Under modified conditions, high-loading Rasta resins (> 3.8 mmol/g) are reproducibly obtained in 40-100 g quantities. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.12.040

文献信息

• Microwave-initiated living free radical polymerization: optimization of the preparative scale synthesis of Rasta resins
  作者：Joseph M. Pawluczyk、Ray T. McClain、Chris Denicola、James J. Mulhearn、Deanne Jackson Rudd、Craig W. Lindsley

  DOI：10.1016/j.tetlet.2006.12.040

  日期：2007.2

  Microwave heating of high-loading TEMPO-methyl resin with functionalized styrenyl monomers in an ADVANCER (TM) preparative scale microwave synthesizer affords larger resin beads (> 375 mu m) via living free radical polymerization (LFRP). Unlike homogeneous MAOS reactions, the heterogeneous LFRP reaction is not directly scalable and required significant optimization. Under modified conditions, high-loading Rasta resins (> 3.8 mmol/g) are reproducibly obtained in 40-100 g quantities. (c) 2006 Elsevier Ltd. All rights reserved.
• Azizian; Krimi, Asian Journal of Chemistry, 2011, vol. 23, # 3, p. 980 - 982
  作者：Azizian、Krimi

  DOI：——

  日期：——