2-环己基-1-甲基哌啶 | 85237-68-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 中文名称: 2-环己基-1-甲基哌啶
• 英文名称: 2-Cyclohexyl-1-methylpiperidine
• CAS: 85237-68-9
• 化学式: C₁₂H₂₃N
• 分子量: 181.32
• InChiKey: NLDMHZIITZOHPA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• [EN] PIPERIDIN-1- YL-N-PYRYDI NE-3-YL-2-OXOACET AM IDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MT A-ACCUMULATING CANCERS<br/>[FR] DÉRIVÉS DE PIPÉRIDIN-1-YL-N-PYRYDINE-3-YL-2-OXO-ACÉTAMIDE UTILES POUR LE TRAITEMENT DE CANCERS DÉFICIENTS EN MTAP ET/OU ACCUMULANT MTA
  申请人：TANGO THERAPEUTICS INC

  公开号：WO2022026892A1

  公开（公告）日：2022-02-03

  Compounds are provided according to Formula (I) and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein R1, R2, R3, R4, R6, R7, R8 and n are as defined herein. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of conditions.

  根据公式（I）提供化合物及其药用盐，以及药物组合物；其中R1、R2、R3、R4、R6、R7、R8和n的定义如本文所述。本发明的化合物被认为对预防和治疗各种疾病条件有用。
• 2-(PIPERIDIN-1-YL)-4-HETEROCYCLYL-THIAZOLE-5-CARBOXYLIC ACID DERIVATIVES AGAINST BACTERIAL INFECTIONS
  申请人：BASARAB Gregory

  公开号：US20120028979A1

  公开（公告）日：2012-02-02

  Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.

  本文描述了公式(I)的化合物及其药学上可接受的盐。还描述了制备它们的过程、包含它们的药物组合物、它们作为药物的用途以及它们在治疗细菌感染中的应用。
• COMPOSITIONS AND METHODS FOR MOLECULAR IMAGING OF OXYGEN METABOLISM
  申请人：Rockland Technimed Ltd.

  公开号：EP2758034A1

  公开（公告）日：2014-07-30
• [EN] COMPOSITIONS AND METHODS USEFUL FOR REALTIME IN SITU PHYSIOLOGICAL MOLECULAR IMAGING OF OXYGEN METABOLISM<br/>[FR] COMPOSITIONS ET PROCÉDÉS UTILES POUR L'IMAGERIE MOLÉCULAIRE PHYSIOLOGIQUE IN SITU EN TEMPS RÉEL DU MÉTABOLISME DE L'OXYGÈNE
  申请人：ROCKLAND TECHNIMED LTD

  公开号：WO2013043236A1

  公开（公告）日：2013-03-28

  Provided are compositions containing an emulsion containing a perfluorinated compound, as well as methods for preparation of the compositions. Also provided are formulations containing a complex of oxygen- 17 and the emulsion. Additionally provided are methods for the preparation of the formulations as well as kits containing the formulations. Further provided are methods of use of the formulations in imaging of tissues using a magnetic resonance imaging system.
• [EN] COMPOSITIONS AND METHODS FOR MOLECULAR IMAGING OF OXYGEN METABOLISM<br/>[FR] COMPOSITIONS ET PROCÉDÉS D'IMAGERIE MOLÉCULAIRE DU MÉTABOLISME DE L'OXYGÈNE
  申请人：ROCKLAND TECHNIMED LTD

  公开号：WO2013044186A1

  公开（公告）日：2013-03-28

  Provided are compositions containing an emulsion containing a perfluorinated compound, as well as methods for preparation of the compositions. Also provided are formulations containing a complex of oxygen- 17 and the emulsion compositions. Additionally provided are methods for the preparation of the formulations as well as kits containing the formulations. Further provided are methods of use of the formulations in imaging of tissues using a magnetic resonance imaging system.