2-甲基-2-丙烯酸聚合丁基2-丙烯酸酯,2-羟基乙基2-甲基-2-丙烯酸酯2-甲基-2-丙烯酸酯和2-丙烯腈 | 71595-57-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 中文名称: 2-甲基-2-丙烯酸聚合丁基2-丙烯酸酯,2-羟基乙基2-甲基-2-丙烯酸酯2-甲基-2-丙烯酸酯和2-丙烯腈
• 中文别名: 十六烷基-N-甲基哌啶鎓
• 英文名称: Hexadecyl-N-methylpiperidinium
• 英文别名: 1-hexadecyl-1-methylpiperidin-1-ium
• CAS: 71595-57-8
• 化学式: C22H46N+
• 分子量: 324.6
• InChiKey: BXVVYPVVDLGLPF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.9
• 重原子数：
  23
• 可旋转键数：
  15
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF
  申请人：Kim Dong Jin

  公开号：US20110124888A1

  公开（公告）日：2011-05-26

  The present invention relates to a novel compound which efficiently inhibits the formation of beta-amyloid fibrils in the brain to be useful for preventing or treating a degenerative brain disease, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient.

  本发明涉及一种新型化合物，能够有效抑制大脑中β-淀粉样蛋白纤维的形成，可用于预防或治疗退行性脑疾病，以及制备该化合物的方法和包含其作为活性成分的药物组合物。
• [EN] AMINOSTYRYLBENZOFURAN DERIVATIVES AS INHIBITORS AGAINST BETA-AMYLOID FIBRIL FORMATION, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME<br/>[FR] DÉRIVÉS AMINOSTYRYLBENZOFURANES EN TANT QU'INHIBITEURS DE LA FORMATION DE FIBRILLES DE BÊTA-AMYLOÏDE, ET COMPOSITION PHARMACEUTIQUE LES CONTENANT
  申请人：KOREA INST SCI & TECH

  公开号：WO2013147568A1

  公开（公告）日：2013-10-03

  The present invention provides an aminostyrylbenzofuran compound of Formula (I), and a pharmaceutical composition comprising same. The pharmaceutical composition of the present invention comprising the compound of Formula (I), a pharmaceutically acceptable salt, an isomer, a hydrate, and a solvate thereof as an active ingredient can be useful for the prevention and treatment of degenerative brain diseases caused by accumulation of beta-amyloid.

  本发明提供了一种式（I）的氨基芳基苯并呋喃化合物，以及包含该化合物的药物组合物。本发明的药物组合物包括式（I）的化合物，药学上可接受的盐，异构体，水合物和溶剂化合物作为活性成分，可用于预防和治疗由β-淀粉样蛋白堆积引起的退行性脑疾病。
• AMINOSTYRYLBENZOFURAN DERIVATIVES AS INHIBITORS AGAINST BETA-AMYLOID FIBRIL FORMATION, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
  申请人：KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

  公开号：US20150065494A1

  公开（公告）日：2015-03-05

  The present invention provides an aminostyrylbenzofuran compound of Formula (I), and a pharmaceutical composition comprising same. The pharmaceutical composition of the present invention comprising the compound of Formula (I), a pharmaceutically acceptable salt, an isomer, a hydrate, and a solvate thereof as an active ingredient can be useful for the prevention and treatment of degenerative brain diseases caused by accumulation of beta-amyloid.

  本发明提供了一种式（I）的氨基芳基呋喃化合物，以及包含该化合物的药物组合物。本发明的药物组合物包括式（I）的化合物，药用可接受的盐，异构体，水合物和溶剂化合物作为活性成分，可用于预防和治疗由β-淀粉样蛋白堆积引起的退行性脑疾病。
• Composition containing a cationic substance and a photoactivator for improved washing and bleaching of fabrics
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0003371A1

  公开（公告）日：1979-08-08

  Combined washing and bleaching of fabrics is accomplished by use of a composition comprising a cationic substance, preferably a surfactant, and a photoactivator. The photoactivator is a porphine or a mono-, di-, tri-, or tetraaza porphine, solubilized with anoinic, nonionic and or cationic substituent groups, and metal free or metallated with Zn(II). Ca(II), Cd(II), Mg(II), Sc(III), Al(III), or Sn(IV).

  织物的水洗和漂白可以通过使用由阳离子物质（最好是表面活性剂）和光活化剂组成的组合物来实现。光活化剂是一种卟吩或单氮、二氮、三氮或四氮卟吩，用阳离子、非离子或阳离子取代基团溶解，不含金属或用 Zn（II）.Ca(II)、Cd(II)、Mg(II)、Sc(III)、Al(III) 或 Sn(IV)。
• Method and use of a composition for cleaning and/or reclaiming printing screens
  申请人：INTERCONTINENTAL CHEMICAL CORPORATION

  公开号：EP0081355A1

  公开（公告）日：1983-06-15

  Method of cleaning and reclaiming printing screens which provide synergistic activities are disclosed. Ink cleaning compositions are also disclosed which degrade or solubilize broad classes of printing ink residues on printing screens for quick removal by a pressurized water stream. The compositions are essentially non-aqueous and contain N-methyl-2-pyrrolidone, an oxygenated solvent, such as butyl cellosolve and cyclohexanone, and a surfactant. The compositions meet health and safety standards due to their biodegradability, lack of flammability and high threshold limit values.

  公开了具有协同作用的清洗和回收印刷网的方法。此外，还公开了油墨清洗组合物，可降解或溶解印刷丝网上的各类印刷油墨残留物，以便用加压水流快速清除。这些组合物基本上是非水性的，含有 N-甲基-2-吡咯烷酮、含氧溶剂（如丁基纤维素溶液和环己酮）和表面活性剂。这些组合物具有生物降解性、不易燃性和较高的阈限值，符合健康和安全标准。