2,6-Dioxopiperidine-4-carboxamide | 887583-72-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 2,6-Dioxopiperidine-4-carboxamide
• CAS: 887583-72-4
• 化学式: C₆H₈N₂O₃
• mdl: MFCD07368056
• 分子量: 156.14
• InChiKey: ZDUKFPJDZKKYIG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.2
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  89.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• PYRROLOPYRAZINE INHIBITORS OF KINASES
  申请人：Abbott Laboratories

  公开号：EP2454262A1

  公开（公告）日：2012-05-23
• [EN] PYRROLOPYRAZINE INHIBITORS OF KINASES<br/>[FR] INHIBITEURS DES PYRROLOPYRAZINES KINASES
  申请人：ABBOTT LAB

  公开号：WO2011008830A1

  公开（公告）日：2011-01-20

  The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein R1a, R1b, X, and Y are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as Cdc7 and methods of treating diseases such as cancer.