1-[8-(triphenylmethylsulfanyl)octyl]piperazine | 337468-25-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: 1-[8-(triphenylmethylsulfanyl)octyl]piperazine
• 英文别名: 1-(8-Tritylsulfanyloctyl)piperazine
• CAS: 337468-25-4
• 化学式: C₃₁H₄₀N₂S
• 分子量: 472.738
• InChiKey: KDTIJEXPBWAJIA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  34
• 可旋转键数：
  13
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  40.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-[8-(triphenylmethylsulfanyl)octyl]piperazine 在 乙酸苯汞 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 8.0h， 生成 bis[8-[4-[(4-(4-methoxycarbonylbenzoyl)piperazino)phenyl]piperazino]octyl] disulfide
  参考文献：
  名称：

  The triphenylmethyl group as thiol protection during ruthenium-promoted synthesis of tetraalkyl-p-phenylenediamine systems having alkanethiol side chains

  摘要：

  The use of triphenylmethyl as thiol protecting group during the construction of thioalkyl-substituted tetraalkyl-p-phenylenediamine derivatives, via arene-ruthenium chemistry, is reported. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(00)01145-5
• 作为产物：
  描述：

  哌嗪 、 1-bromo-8-(triphenylmethylsulfanyl)octane 以 乙醇 为溶剂， 以98%的产率得到1-[8-(triphenylmethylsulfanyl)octyl]piperazine
  参考文献：
  名称：

  The triphenylmethyl group as thiol protection during ruthenium-promoted synthesis of tetraalkyl-p-phenylenediamine systems having alkanethiol side chains

  摘要：

  The use of triphenylmethyl as thiol protecting group during the construction of thioalkyl-substituted tetraalkyl-p-phenylenediamine derivatives, via arene-ruthenium chemistry, is reported. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(00)01145-5

文献信息

• The triphenylmethyl group as thiol protection during ruthenium-promoted synthesis of tetraalkyl-p-phenylenediamine systems having alkanethiol side chains
  作者：Anthony J. Pearson、Jiunn-Jye Hwang

  DOI：10.1016/s0040-4020(00)01145-5

  日期：2001.2

  The use of triphenylmethyl as thiol protecting group during the construction of thioalkyl-substituted tetraalkyl-p-phenylenediamine derivatives, via arene-ruthenium chemistry, is reported. (C) 2001 Elsevier Science Ltd. All rights reserved.