Bromomethyl-[9-[tert-butyl(dimethyl)silyl]oxynon-1-en-5-yn-4-yloxy]-dimethylsilane | 198287-19-3

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: Bromomethyl-[9-[tert-butyl(dimethyl)silyl]oxynon-1-en-5-yn-4-yloxy]-dimethylsilane
• 英文别名: bromomethyl-[9-[tert-butyl(dimethyl)silyl]oxynon-1-en-5-yn-4-yloxy]-dimethylsilane
• CAS: 198287-19-3
• 化学式: C₁₈H₃₅BrO₂Si₂
• 分子量: 419.55
• InChiKey: CKIMZYVSKWQSCN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.89
• 重原子数：
  23
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  甲基锂 、 Bromomethyl-[9-[tert-butyl(dimethyl)silyl]oxynon-1-en-5-yn-4-yloxy]-dimethylsilane 在 偶氮二异丁腈 、 三正丁基氢锡 作用下， 生成
  参考文献：
  名称：

  Design of a radical translocation step through 1, n (n = 5, 6, 7) hydrogen transfers for incorporation into new radical cascades

  摘要：

  The scope and limitations in the 1,n (n = 5, 6, 7) hydrogen transfers from homoallyl radicals of type 10 have been delineated. Encouraging results have notably been obtained with a dioxolane on the side chain to promote a 1,6-H transfer and with a TBS ether to promote a 1,5-H transfer. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00899-5
• 作为产物：
  描述：

  1-(tert-butyldimethylsilyloxy)-4-pentyne 在 六甲基磷酰三胺 、 4-二甲氨基吡啶 、 正丁基锂 、 1,10-菲罗啉 、 乙基溴化镁 、 三乙胺 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 反应 0.92h， 生成 Bromomethyl-[9-[tert-butyl(dimethyl)silyl]oxynon-1-en-5-yn-4-yloxy]-dimethylsilane
  参考文献：
  名称：

  Design of a radical translocation step through 1, n (n = 5, 6, 7) hydrogen transfers for incorporation into new radical cascades

  摘要：

  The scope and limitations in the 1,n (n = 5, 6, 7) hydrogen transfers from homoallyl radicals of type 10 have been delineated. Encouraging results have notably been obtained with a dioxolane on the side chain to promote a 1,6-H transfer and with a TBS ether to promote a 1,5-H transfer. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00899-5

文献信息

• Design of a radical translocation step through 1, n (n = 5, 6, 7) hydrogen transfers for incorporation into new radical cascades
  作者：Alexandre Gross、Louis Fensterbank、Stéphane Bogen、René Thouvenot、Max Malacria

  DOI：10.1016/s0040-4020(97)00899-5

  日期：1997.10

  The scope and limitations in the 1,n (n = 5, 6, 7) hydrogen transfers from homoallyl radicals of type 10 have been delineated. Encouraging results have notably been obtained with a dioxolane on the side chain to promote a 1,6-H transfer and with a TBS ether to promote a 1,5-H transfer. (C) 1997 Elsevier Science Ltd.