bis-(3-piperidino-propyl)-amine | 854253-57-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: bis-(3-piperidino-propyl)-amine
• 英文别名: Bis-(3-piperidino-propyl)-amin；3-piperidin-1-yl-N-(3-piperidin-1-ylpropyl)propan-1-amine
• CAS: 854253-57-9
• 化学式: C₁₆H₃₃N₃
• 分子量: 267.458
• InChiKey: YBPHGEKIWUXBPQ-UHFFFAOYSA-N

物化性质

• 沸点：
  184-188 °C(Press: 8-9 Torr)
• 密度：
  0.943±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  bis-(3-piperidino-propyl)-amine 、 对乙酰胺基苯磺酰氯 在 potassium carbonate 、 丙酮 作用下， 生成 sulfanilic acid-[bis-(3-piperidino-propyl)-amide]
  参考文献：
  名称：

  Basically Substituted Aliphatic Nitriles and their Catalytic Reduction to Amines¹

  摘要：

  DOI：

  10.1021/ja01233a019
• 作为产物：
  描述：

  哌啶 在 镍 作用下， 120.0 ℃ 、9.81 MPa 条件下， 生成 bis-(3-piperidino-propyl)-amine
  参考文献：
  名称：

  Basically Substituted Aliphatic Nitriles and their Catalytic Reduction to Amines¹

  摘要：

  DOI：

  10.1021/ja01233a019

文献信息

• [EN] BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR<br/>[FR] INHIBITEURS DE TRIAZOLE BIARYLE DU FACTEUR INHIBITEUR DE LA MIGRATION DES MACROPHAGES
  申请人：UNIV YALE

  公开号：WO2016130968A1

  公开（公告）日：2016-08-18

  The present disclosure describes biaryl triazole compounds, as well as their compositions and methods of use. The compounds inhibit the activity of macrophage migration inhibitory factor and are useful for the treatment of diseases, e.g., inflammatory diseases and cancer.

  本公开描述了联苯三唑化合物，以及它们的组合物和使用方法。这些化合物抑制巨噬细胞迁移抑制因子的活性，并且对于治疗疾病，例如炎症性疾病和癌症，具有用处。
• Optical data medium containing, in the information layer, a phthalocyanine dye as a light-absorbing compound
  申请人：——

  公开号：US20020076648A1

  公开（公告）日：2002-06-20

  The invention relates to an optical data medium containing a preferably transparent substrate that is optionally already coated with one or more reflective layers and on the surface of which have been applied: (1) an information layer that can be recorded on using light, wherein the information layer contains at least one phthalocyanine light-absorbing compound and optionally a binder, (2) optionally one or more reflective layers, and (3) optionally a protective layer or a further substrate or a covering layer wherein the optical data medium can be recorded on and read using blue light, preferably laser light.

  本发明涉及一种光学数据介质，该介质包含一个最好是透明的基底，该基底可选地已经涂有一层或多层反射层，并在其表面涂有以下涂层： (1) 可以用光记录的信息层，其中信息层含有至少一种酞菁光吸收化合物和粘合剂、 (2) 可选的一个或多个反射层，以及 (3) 可选的保护层或进一步的基底或覆盖层 其中，光学数据介质可以用蓝光（最好是激光）记录和读取。
• Optical data stores containing a Co-phthalocyanine complex in the information layer recordable using light
  申请人：——

  公开号：US20020127366A1

  公开（公告）日：2002-09-12

  The present invention relates to a singly recordable optical data medium using Co-phthalocyanine complexes of the formula (I) 1 In which the groups are defined herein, as light-absorbing compounds in the information layer of optical data media, in which information layer is recordable using light, particularly for CD-R, and the application of the above-mentioned compounds to a polymer substrate, particularly polycarbonate, by spin coating.

  本发明涉及一种使用式 (I) 共酞菁配合物的单次可记录光学数据介质 1 其中的基团在此定义，作为光学数据介质信息层中的光吸收化合物，其中的信息层可使用光进行记录，特别是用于 CD-R，以及通过旋涂将上述化合物应用于聚合物基材，特别是聚碳酸酯。
• Optical data store comprising an axially substituted cobalt phthalocyanine in the light-writeable information layer
  申请人：——

  公开号：US20020172793A1

  公开（公告）日：2002-11-21

  Optical data carrier comprising a preferably transparent substrate which may, if desired, have previously been coated with one or more reflection layers and to whose surface a light-writeable information layer, if desired one or more reflection layers and if desired a protective layer or a further substrate or a covering layer have been applied, which can be written on and read by means of infrared light, preferably laser light, particularly preferably light having a wavelength in the range 750-800 nm, in particular 770-790 nm, where the information layer comprises a light-absorbent compound and, if desired, a binder, characterized in that at least one cobalt(III) phthalocyanine in which the Co metal centre bears two axial substituents R 1 and R 2 which represent, independently of one another, CN, SCN, alkoxy or alkylthio is used as light-absorbent compound.

  光学数据载体，包括一个最好是透明的基底，如果需要，该基底可以事先涂有一层或多层反射层，其表面涂有可光写的信息层，如果需要，还可以涂有一层或多层反射层，如果需要，还可以涂有保护层或另一层基底或覆盖层、信息层包括光吸收化合物，如果需要，还包括粘合剂，其特征在于至少有一种酞菁钴（III），其中的钴金属中心带有两个轴向取代基 R 1 和 R 2 分别代表 CN、SCN、烷氧基或烷基硫代）的酞菁作为光吸收化合物。
• Optical data medium containing, in the information layer, a dye as a light-absorbing compound
  申请人：——

  公开号：US20030113665A1

  公开（公告）日：2003-06-19

  Optical data medium containing a preferably transparent substrate which is optionally already coated with one or more barrier layers and on the surface of which an information layer which can be recorded on using light, optionally one or more barrier layers, and a cover layer, have been applied, which data medium can be recorded on and read using focused blue light through the cover layer on the information layer, preferably laser light with the wavelength between 360 nm and 460 nm, the information layer containing a light-absorbing compound and optionally a binder, characterized in that at least one dye is used as the light-absorbing compound wherein the cover layer on the top of the information layer including the adhesive layer do have a total thickness of 10 &mgr;m to 177 &mgr;m and the numerical aperture NA of the focusing objective lens setup is greater or equal 0.8.

  光学数据介质，包含一个最好是透明的基底，该基底上可能已经涂有一层或多层阻挡层，在该基底的表面涂有可以用光记录的信息层，可能还有一层或多层阻挡层，以及一个覆盖层，该数据介质可以用聚焦蓝光通过覆盖层记录在信息层上并读取、其中，信息层顶部的覆盖层（包括粘合剂层）的总厚度为 10 &mgr；m至177&mgr;m，聚焦物镜设置的数值孔径NA大于或等于0.8.