3-(2-吡咯烷基)哌啶 | 858262-19-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 中文名称: 3-(2-吡咯烷基)哌啶
• 中文别名: 3-(2-吡咯烷基)哌啶,97
• 英文名称: 3-pyrrolidin-2-yl-piperidine
• 英文别名: 3-Pyrrolidin-2-yl-piperidin；3-Pyrrolidin-2-ylpiperidine
• CAS: 858262-19-8
• 化学式: C₉H₁₈N₂
• 分子量: 154.255
• InChiKey: QLTZNGNUWYPOSS-UHFFFAOYSA-N

物化性质

• 沸点：
  233.1±8.0 °C(Predicted)
• 密度：
  0.958±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  24.1
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 危险等级：
  8
• 海关编码：
  2933990090
• 危险品运输编号：
  UN 3259

反应信息

• 作为产物：
  描述：

  3-(吡咯烷-2-基)吡啶 在 盐酸 、 铂 作用下， 生成 3-(2-吡咯烷基)哌啶
  参考文献：
  名称：

  Haines et al., Journal of the American Chemical Society, 1945, vol. 67, p. 1258,1260

  摘要：

  DOI：

文献信息

• [EN] ß-LACTONE COMPOUNDS<br/>[FR] COMPOSÉS DE ß-LACTONE
  申请人：UNIV OXFORD INNOVATION LTD

  公开号：WO2019111020A1

  公开（公告）日：2019-06-13

  The present invention relates to certain β-lactone compounds that may be useful as inhibitors of bacterial beta-lactamases. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of a bacterial infection.

  本发明涉及某些β-内酰胺类化合物，可用作细菌β-内酰胺酶的抑制剂。本发明还涉及制备这些化合物的过程，包括它们的制药组合物，并且涉及它们在治疗细菌感染中的使用。
• Composition and methods for producing tobacco plants and products having reduced tobacco-specific nitrosamines (TSNAs)
  申请人：Altria Client Services LLC

  公开号：US10647989B2

  公开（公告）日：2020-05-12

  The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radical absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.

  本公开提供了减少烟草中烟草特异性亚硝胺（TSNAs）的方法。其中一些方法包括对烟草植物进行基因工程改造，以增加一种或多种抗氧化剂、提高氧自由基吸收能力（ORAC）或减少亚硝酸盐。此外，还提供了生产改良烟草植物及其烟草产品的方法和组合物，其中包含减少的 TSNAs。
• Handheld microcantilever-based sensor for detecting tobacco-specific nitrosamines
  申请人：Deevi C. Seetharama

  公开号：US20080102532A1

  公开（公告）日：2008-05-01

  A method and system for detecting tobacco-specific nitrosamines. The method includes exposing at least one microcantilever beam to a medium, which may contain tobacco-specific nitrosamines, and measuring a deflection of the microcantilever beam, wherein the deflection indicates a presence of tobacco-specific nitrosamines in the medium. The at least one microcantilever beam can include a silicon base layer and a gold-coated receptor layer with a plurality of thiol molecules having a sulfur head and carboxyl-terminated group. The at least one microcantilever beam can include a silicon base layer and a metal or metal oxide coated receptor layer. Alternatively, the microcantilever beam can be formed by co-absorbing tobacco-specific nitrosamines and silane molecules on a silicon microcantilever surface, wherein the template molecules of tobacco-specific nitrosamines physically co-adsorb between the silane molecules. The template molecules of tobacco-specific nitrosamines are then washed away with a solvent to form a silane monolayer having tobacco-specific nitrosamine cavities.
• US7709264B2
  申请人：——

  公开号：US7709264B2

  公开（公告）日：2010-05-04
• [EN] POLYAMINE COMPOUNDS AND METAL COMPLEXES COMPRISING SAME FOR THE USE THEREOF AS ANTIPARASITIC AGENTS<br/>[ES] COMPUESTOS POLIAMÍNICOS Y COMPLEJOS METÁLICOS QUE LOS COMPRENDEN PARA SU USO COMO AGENTES ANTIPARASITARIOS<br/>[FR] COMPOSÉS DE POLYAMINE ET COMPLEXES MÉTALLIQUES LES CONTENANT, POUR APPLICATION COMME AGENTS ANTIPARASITAIRES
  申请人：UNIV GRANADA

  公开号：WO2015059337A1

  公开（公告）日：2015-04-30

  La presente invención se refiere al uso de compuestos de base poliamínica o de sus complejos metálicos para la prevención y/o el tratamiento de enfermedades de origen parasitario como por ejemplo la Tripanosomiasis americana también conocida como enfermedad de Chagas o la Leishmaniasis.