1-(2,3-dihydro-1H-indol-1-yl)-2-(piperazin-1-yl)ethan-1-one | 1018497-78-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 1-(2,3-dihydro-1H-indol-1-yl)-2-(piperazin-1-yl)ethan-1-one
• 英文别名: 1-(2,3-dihydroindol-1-yl)-2-piperazin-1-ylethanone
• CAS: 1018497-78-3
• 化学式: C₁₄H₁₉N₃O
• mdl: MFCD10011126
• 分子量: 245.32
• InChiKey: OJPWNCPVNIQBOC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  35.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Indoline derivatives and method for using and producing the same
  申请人：ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

  公开号：US10654802B2

  公开（公告）日：2020-05-19

  The present invention relates to a compound of the formula: where n, R1 and R2 are those defined herein. The present invention also relates to use of a compound of Formula 1 in treating a clinical condition associated with fibrotic disorder.

  本发明涉及式 1 的化合物，其中 n、R1 和 R2 为本文所定义者。本发明还涉及式 1 化合物在治疗与纤维化紊乱有关的临床病症中的用途。
• INDOLINE DERIVATIVES AND METHOD FOR USING AND PRODUCING THE SAME
  申请人：ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

  公开号：US20190135746A1

  公开（公告）日：2019-05-09

  The present invention relates to a compound of the formula: where n, R and R are those defined herein. The present invention also relates to use of a compound of Formula 1 in treating a clinical condition associated with fibrotic disorder.