m-cresolsulfonphthalein | 928715-39-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 英文名称: m-cresolsulfonphthalein
• 英文别名: 2,2'-(1,1-Dioxido-3H-2,1-benzoxathiol-3-ylidene)bis[5-methylphenol]；2-[3-(2-hydroxy-4-methylphenyl)-1,1-dioxo-2,1λ6-benzoxathiol-3-yl]-5-methylphenol
• CAS: 928715-39-3
• 化学式: C₂₁H₁₈O₅S
• 分子量: 382.437
• InChiKey: IDZSDOZKMHWZGH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  27
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  92.2
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• N-acetyl-beta-D-glucosaminides for determining N-acetyl-beta-D-glucosaminidase activity
  申请人：SHIONOGI & CO., LTD.

  公开号：EP0060793A1

  公开（公告）日：1982-09-22

  N-Acetyl-p-D-glucosaminides produced from 1-chloro-1-deoxy-2,3,4,6-tetraacetyl-a-D-glucosamine and indicators for titration as the aglycons useful as substrates in kits for diagnostic aid, with which N-acetyl-p-D-glucosaminidase activity can be determined colorimetrically in high sensitivity, precisely, and quickly.

  由 1-氯-1-脱氧-2,3,4,6-四乙酰-a-D-葡糖胺和滴定指示剂制成的 N-乙酰基-p-D-葡糖胺苷，可用作诊断辅助试剂盒中的底物，用它可以用比色法高灵敏度、精确、快速地测定 N-乙酰基-p-D-葡糖胺苷酶的活性。
• Method and kit for testing polyolester lubricants used in refrigerant compressors
  申请人：THERMO KING CORPORATION

  公开号：EP0867719A1

  公开（公告）日：1998-09-30

  Both a method and a kit for testing the fitness of a polyolester lubricant of the type used in a refrigerant compressor are provided. In the method of the invention, a solution for indicating an excess acidity of the polyolester lubricant is obtained by mixing a color acidity indicator, such as alizarin, with a sufficient amount of an alkaline to neutralize the inherent acidity of the lubricant. The resulting solution changes color only upon the presence of an excess acid condition associated with a compressor malfunction, such as burn out. Both the method and the kit are particularly well adapted to determine the fitness of polyolester lubricants of the type prepared by the reaction of trimethylolpropane with a mixture of a branched and a linear acid.

  本发明提供了一种方法和一种工具包，用于测试制冷剂压缩机中使用的聚烯烃润滑剂的适用性。在本发明的方法中，通过将颜色酸度指示剂（如茜素）与足量的碱性物质混合以中和润滑剂的固有酸性，可获得用于指示聚烯烃润滑剂酸度过高的溶液。只有在出现与压缩机故障（如烧毁）相关的过量酸性条件时，所得溶液才会变色。该方法和试剂盒尤其适用于测定由三羟甲基丙烷与支链酸和线性酸混合物反应制备的聚胆固醇润滑剂的适用性。
• System for the detection of urease and method for using same
  申请人：Marshall, Barry

  公开号：EP1918712A1

  公开（公告）日：2008-05-07

  A system and method for detecting bacterial infections in the gastrointestinal tract is disclosed. In one embodiment, the system includes a first composition separated from a second composition. The first composition contains urea in powdered form. The second composition, on the other hand, contains an indicator. A biopsy of a gastric sample is first contacted with the first composition and then placed in the second composition. The second composition indicates the presence of an enzyme that, in turn, indicates the presence of bacteria. In an alternative embodiment of the present invention, a biopsy of a gastric sample is contacted with a single composition. The composition contains urea in a powdered form combined with a dry indicator. Besides urea and a dry indicator, the composition can also contain an anti-caking agent. The system of the present invention can include a container for holding the composition. A specimen handling tool can be included in the container for handling a biopsy sample.

  本文公开了一种检测胃肠道细菌感染的系统和方法。在一个实施方案中，该系统包括与第二组合物分离的第一组合物。第一种组合物含有粉末状的尿素。第二种成分则含有指示剂。胃活检样本首先与第一种组合物接触，然后放入第二种组合物中。第二种组合物会显示一种酶的存在，而这种酶又会显示细菌的存在。在本发明的另一个实施方案中，胃样本活检组织与单一组合物接触。这种组合物含有粉末状的尿素和干指示剂。除尿素和干性指示剂外，组合物还可含有抗结块剂。本发明的系统可以包括一个用于容纳组合物的容器。容器中可包括一个标本处理工具，用于处理活检样本。
• Selective inhibition of C4-PEP carboxylases
  申请人：Heinrich Heine Universität Düsseldorf

  公开号：US10188107B2

  公开（公告）日：2019-01-29

  The present invention relates to the use of a compound, a salt or solvate thereof as C4 plant selective herbicide wherein said compound has a structure according to formula (I) wherein A is a cyclic alkyl, aryl, heterocycloalkyl, or heteroaryl group, and B is a cyclic alkyl, aryl, heterocycloalkyl, or heteroaryl group, and wherein R1, R2, R3, R4 and R5 are, independently of each other H or an alkyl group, and wherein integer i is 0 or 1, preferably 1, and the bond (a) is a single or double bond, and wherein in case (a) is a double bond, n is 0 and X is O or S, and wherein in case (a) is a single bond n is 1, and X is H or an alkyl group, and wherein the bond (b) is a single or double bond, and wherein in case (b) is a double bond, m and p are 0, and wherein in case (b) is a single bond m and p are both 1, and/or according to formula (II) including tautomeric structures thereof, wherein R01 and R02 are independently of each other selected from the group consisting of H, OH, carboxylic acid, ester, alkyl, alkoxy and halogen, wherein Y1 is selected from the group consisting of (S(═O)2), S(═O)) and (C(═O)), and wherein Y2 is O, and wherein r is 0 or 1 and wherein in case r is 0, q and s are 1, and wherein in case r is 1, q and s are 0, and wherein R01, R02, R04, R05, R06, R07, R04#, R05#, R06#, R07#, R09, R010, R011 and R012 are independently of each other selected from the group consisting of H, OH, —SO3H, carboxylic acid, ester, alkyl, alkoxy and halogen, said compound being capable of binding to the malate binding site comprised by a phosphoenolpyruvate carboxylase from a C4 plant, thereby inhibiting said phosphoenolpyruvate carboxylase.

  本发明涉及一种化合物、其盐或溶液作为 C4 植物选择性除草剂的用途，其中所述化合物具有符合式 (I) 的结构，其中 A 是环烷基、芳基、杂环烷基或杂芳基，B 是环烷基、芳基、杂环烷基或杂芳基，R1、R2、R3、R4 和 R5 相互独立地为 H 或烷基、其中整数 i 为 0 或 1，优选 1，键（a）为单键或双键，在（a）为双键的情况下，n 为 0，X 为 O 或 S，在（a）为单键的情况下，n 为 1，X 为 H 或烷基，键（b）为单键或双键，在（b）为双键的情况下，m 和 p 为 0，在（b）为单键的情况下，m 和 p 均为 1、和/或根据式（II），包括其同分异构体结构，其中 R01 和 R02 各自独立地选自 H、OH、羧酸、酯、烷基、烷氧基和卤素组成的组、其中 Y1 选自（S(═O)2）、S(═O)）和（C(═O)）组成的组，Y2 为 O，r 为 0 或 1，在 r 为 0 的情况下，q 和 s 为 1，在 r 为 1 的情况下、其中 R01、R02、R04、R05、R06、R07、R04#、R05#、R06#、R07#、R09、R010、R011 和 R012 相互独立地选自 H、OH、-SO3H、羧酸、酯、烷基、烷氧基和卤素组成的组、烷基、烷氧基和卤素，所述化合物能够与来自 C4 植物的磷酸烯醇丙酮酸羧化酶所包含的苹果酸结合位点结合，从而抑制所述磷酸烯醇丙酮酸羧化酶。
• Method for the detection of urease and method for using same
  申请人：Kimberly-Clark Worldwide, Inc.

  公开号：US20030077680A1

  公开（公告）日：2003-04-24

  A system and method for detecting bacterial infections in the gastrointestinal tract is disclosed. In one embodiment, the system includes a first composition separated from a second composition. The first composition contains urea in powdered form. The second composition, on the other hand, contains an indicator. A biopsy of a gastric sample is first contacted with the first composition and then placed in the second composition. The second composition indicates the presence of an enzyme that, in turn, indicates the presence of bacteria. In an alternative embodiment of the present invention, a biopsy of a gastric sample is contacted with a single composition. The composition contains urea in a powdered form combined with a dry indicator. Besides urea and a dry indicator, the composition can also contain an anti-caking agent.

  本文公开了一种检测胃肠道细菌感染的系统和方法。在一个实施方案中，该系统包括与第二组合物分离的第一组合物。第一种组合物含有粉末状的尿素。第二种成分则含有一种指示剂。胃活检样本首先与第一种组合物接触，然后放入第二种组合物中。第二种组合物会显示一种酶的存在，而这种酶又会显示细菌的存在。在本发明的另一个实施方案中，胃样本活检组织与单一组合物接触。这种组合物含有粉末状的尿素和干指示剂。除尿素和干性指示剂外，组合物还可含有抗结块剂。