3-乙氧基噻吩-2-羧肼 | 175137-40-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 中文名称: 3-乙氧基噻吩-2-羧肼
• 英文名称: 3-Ethoxythiophene-2-carbohydrazide
• CAS: 175137-40-3
• 化学式: C₇H₁₀N₂O₂S
• mdl: MFCD00205206
• 分子量: 186.23
• InChiKey: ZUNYIBQGLXMFFG-UHFFFAOYSA-N

物化性质

• 密度：
  1.267±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.285
• 拓扑面积：
  92.6
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2934999090

文献信息

• SELECTIVE ANTIBACTERIAL AGENTS
  申请人：4SC AG

  公开号：EP1478364A2

  公开（公告）日：2004-11-24
• [EN] SELECTIVE ANTIBACTERIAL AGENTS<br/>[FR] AGENTS ANTIBACTERIENS SELECTIFS
  申请人：4SC AG

  公开号：WO2003039549A2

  公开（公告）日：2003-05-15

  The present invention relates to the use of compounds of the general Formula (I), for the regulation of the quorum sensing system of microorganisms wherein in Formula (I), R is H, alkyl, cycloalkyl, aryl or heteroaryl; R1 is H, alkyl, cycloalkyl, aryl or heteroaryl; R2 is H, alkyl, cycloalkyl, aryl or heteroaryl; A?1 and A2¿ each independently represent an optionally substituted C¿1?-C20-alkyl group which may contain one or more group(s) Z, or a monocyclic or polycyclic optionally substituted aromatic or non-aromatic ring system which may contain one or more group(s) X, and in case of a polycyclic ring system, said system contains at least one aromatic ring; Z is selected from the group consisting of S, O, N, NR?4¿, CO, CO¿2?, CS, SO or SO2 X is selected from the group consisting of S, O, N, NR?4¿, SO or SO¿2?; said substituted ring system carries a substituent R?3¿ on one or more of the carbon atoms of said ring system;said substituted C¿1?-C20-alkyl group carries a substituent R?3¿ on one or more of the carbon atoms of said alkyl group; R3 is independently H, OR4, SR4, hydroxyalkyl, hydroxyalkylamino, cycloalkyl, halogen, haloalkyl, haloalkyloxy, NO¿2?, CN, SO2NR?4R5, CO¿2NR?4R5, COR4, CO¿2R4, SO2R4, SO3R?4, NR4R5¿, alkyl, aryl or heteroaryl; R4 is H, alkyl, cycloalkyl, aryl or heteroaryl; R5 is H, O-alkyl, O-aryl, alkyl, heteroaryl or aryl; Y?1 and Y2¿ are independent from each other C=O, C=S, SO2 or C=NR5; p is 0, m is 0, n is 0; or p is 0, m is 0, n is 1;or p is 0, m is 1, n is 1; or p is 1, m is 0, n is 0; or p is 1, m is 0, n is 1; or p is 1, m is 1, n is 1.