申请人:Gwangju Institute of Science and Technology
公开号:EP2600147A2
公开(公告)日:2013-06-05
The present invention provides a method for screening a diabetes treating agent comprising the following steps: (a) preparing cells inside a culture medium; (b) treating the culture medium with a test substance; (c) treating the result of step (b) with a glucose derivative which is not metabolized; and (d) measuring the glucose derivative which has flowed into the cells, wherein the test substance is determined to be a diabetes treating agent if the test substance accelerates uptake of the glucose derivative in the cells. Therefore, the described pharmaceutical composition, including a triazin-based compound as an active ingredient, can be useful for application in preventing or treating diabetes.
本发明提供了一种筛选糖尿病治疗药物的方法,包括以下步骤:(a) 在培养基内制备细胞;(b) 用试验物质处理培养基;(c) 用未代谢的葡萄糖衍生物处理步骤(b)的结果;(d) 测量流入细胞的葡萄糖衍生物,其中,如果试验物质加速了细胞对葡萄糖衍生物的吸收,则确定该试验物质为糖尿病治疗剂。因此,所述药物组合物(包括作为活性成分的三嗪类化合物)可用于预防或治疗糖尿病。