NBD-双十六胺 | 117056-66-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶二唑类
• 中文名称: NBD-双十六胺
• 英文名称: 4-Benzofurazanamine, N,N-dihexadecyl-7-nitro-
• 英文别名: N,N-dihexadecyl-4-nitro-2,1,3-benzoxadiazol-7-amine
• CAS: 117056-66-3
• 化学式: C38H68N4O3
• 分子量: 629.0
• InChiKey: JVTZCQBNIYPZGI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  16.6
• 重原子数：
  45
• 可旋转键数：
  31
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  88
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• Lipoparticles comprising proteins, methods of making, and using the same
  申请人：Doranz J. Benjamin

  公开号：US20050123563A1

  公开（公告）日：2005-06-09

  The present invention relates to lipoparticles. The invention also relates to producing lipoparticles. The invention further relates to lipoparticles comprising a viral structural protein. The invention further relates to a lipoparticle comprising a membrane protein, and the lipoparticle can be attached to a sensor surface. The invention further relates to methods of producing and using the lipoparticle to, inter alia, assess protein binding interactions.

  本发明涉及脂质颗粒。本发明还涉及脂质颗粒的生产。本发明还涉及包含病毒结构蛋白的脂质颗粒。本发明进一步涉及一种包含膜蛋白的脂质颗粒，该脂质颗粒可附着在传感器表面。本发明进一步涉及生产和使用脂质颗粒的方法，以评估蛋白质结合相互作用等。
• Modulators of retinol-retinol binding protein (RBP)-transthyretin (TTR) complex formation
  申请人：Mata L. Nathan

  公开号：US20060094063A1

  公开（公告）日：2006-05-04

  Described herein are methods and compositions for the detection of transthyretin (TTR), retinol binding protein (RBP) and retinol complex formation. The methods and compositions described herein also provide for the screening of modulators of retinol-RBP-TTR complex formation. Furthermore, the methods and compositions provide for therapeutic agents for the treatment and/or prevention of age-related macular degeneration and/or dystrophies.

  本文描述的是检测转甲状腺素（TTR）、视黄醇结合蛋白（RBP）和视黄醇复合物形成的方法和组合物。本文所述的方法和组合物还可用于筛选视黄醇-RBP-TTR 复合物形成的调节剂。此外，这些方法和组合物还提供了治疗和/或预防老年性黄斑变性和/或营养不良的治疗剂。
• LIPOPARTICLES COMPRISING PROTEINS, METHODS OF MAKING, AND USING THE SAME
  申请人：Integral Molecular, Inc.

  公开号：EP1660638B1

  公开（公告）日：2015-12-23
• Modulators of Retinol-Retinol Binding Protein (RBP)-Transthyretin (TTR) Complex Formation
  申请人：Mata Nathan L.

  公开号：US20090054532A1

  公开（公告）日：2009-02-26

  Described herein are methods and compositions for the detection of transthyretin (TTR), retinol binding protein (RBP) and retinol complex formation. The methods and compositions described herein also provide for the screening of modulators of retinol-RBP-TTR complex formation. Furthermore, the methods and compositions provide for therapeutic agents for the treatment and/or prevention of age-related macular degeneration and/or dystrophies.
• MODULATORS OF RETINOL-RETINOL BINDING PROTEIN (RBP)-TRANSTHYRETIN (TTR) COMPLEX FORMATION
  申请人：Mata Nathan L.

  公开号：US20120238632A1

  公开（公告）日：2012-09-20

  Described herein are methods and compositions for the detection of transthyretin (TTR), retinol binding protein (RBP) and retinol complex formation. The methods and compositions described herein also provide for the screening of modulators of retinol-RBP-TTR complex formation. Furthermore, the methods and compositions provide for therapeutic agents for the treatment and/or prevention of age-related macular degeneration and/or dystrophies.