3-甲基-5,6-二苯基-1,2,4-三嗪 | 24108-37-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 中文名称: 3-甲基-5,6-二苯基-1,2,4-三嗪
• 英文名称: 3-methyl-5,6-diphenyl-1,2,4-triazine
• 英文别名: 5,6-diphenyl-3-methyl-1,2,4-triazine；3-methyl-5,6-diphenyl-as-triazine；5,6-diphenyl-3-methyl-as-triazine；3-methyl-5,6-diphenyl-[1,2,4]triazine；3-Methyl-5,6-diphenyl-[1,2,4]triazin
• CAS: 24108-37-0
• 化学式: C₁₆H₁₃N₃
• 分子量: 247.299
• InChiKey: WOWXDXVLJFZZQB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  38.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-甲基-5,6-二苯基-1,2,4-三嗪 在 chlirine 、 硫酸 、 sodium acetate 作用下， 以 甲醇 、 溶剂黄146 为溶剂， 生成 安息香甲基醚
  参考文献：
  名称：

  Konno, Shoetsu; Yokoyama, Masaaki; Yamanaka, Hiroshi, Heterocycles, 1982, vol. 19, # 10, p. 1865 - 1868

  摘要：

  DOI：
• 作为产物：
  描述：

  苯偶酰腙 在 乙醇 、 氨 作用下， 生成 3-甲基-5,6-二苯基-1,2,4-三嗪
  参考文献：
  名称：

  Metze; Meyer, Chemische Berichte, 1957, vol. 90, p. 481,484

  摘要：

  DOI：

文献信息

• Monomer 5, 6-Diphenyl-1.2.4-Traizinic Derivatives and the Use Thereof
  申请人：Rey Jerome

  公开号：US20080299055A1

  公开（公告）日：2008-12-04

  The invention relates to the use of 5,6-diphenyl-1,2,4-triazinic compounds of general formula (I), wherein cycle penetrating bonds display an ortho, meta or para indifferent substitution position, identical or different R 1 and R 2 represent a hydrogen, fluoride, chloride or bromine atom, C 1 to C 12 linear or branched alkyl, C 1 A C 18 linear or branched hydroxy, alkoxy poly(ethoxy)-alkoxy with a C 1 to C 4 alkyl fragment and an ethoxy number ranging from 1 to 4, amino or mono or di-alkylamino with a C 1 to C 4 alkyl fragment group, R 3 represents a chlorine atom, a hydroxy, amino, a phenyl possibly 1 to 3 times substituted by a hydroxy radical situated at least in a para or phenyl position possibly 1 to 3 times substituted in an ortho, meta or para position by a C 1 to C 12 alkoxy or cyano or alkymino group with a C 1 to C 7 alkyl fragment in the form of active sun filters or light-protective agents and to cosmetic composition containing said compounds.

  该发明涉及使用通式(I)的5,6-二苯基-1,2,4-三唑化合物，其中环穿透键显示一个邻位、间位或对位的不同取代位置，相同或不同的R1和R2代表氢、氟、氯或溴原子，C1至C12直链或支链烷基，C1至C18直链或支链羟基、烷氧基聚（乙氧基）-烷氧基，具有从1到4的乙氧基数的C1至C4烷基片段和氨基或单或双烷基氨基，具有C1至C4烷基片段的羟基、氨基、苯基，可能被羟基取代1到3次，位于对位或苯基位置，可能被C1至C12烷氧基或氰基或烷基氨基团取代1到3次，形式为活性防晒剂或光保护剂的化妆品组合物中含有所述化合物。
• Arylation of 1,2,4-Triazines in the Presence of AlCl₃
  作者：Ilya N. Egorov

  DOI：10.5560/znb.2014-4103

  日期：2014.8.1

  This paper presents a method for introducing toluene and bromobenzene moieties into 1,2,4- triazines as an alternative to cross-coupling reactions. It is demonstrated that the C=N bond of a wide range of 1,2,4-triazines undergoes addition of arenes in the presence of AlCl₃.

  本文介绍了一种将甲苯和溴苯分子引入 1,2,4-三嗪的方法，以替代交叉耦合反应。研究表明，在 AlCl3 的存在下，多种 1,2,4-三嗪的 C=N 键会发生茴香加成反应。
• Protease detection material, set of protease detection materials, and method for measuring protease
  申请人：FUJIFILM Corporation

  公开号：EP2107122A1

  公开（公告）日：2009-10-07

  The present invention provides a protease detection material having, on a support, at least a layer containing a dye precursor and a layer which contains a protease substrate and is disposed on the same side of the support as the layer containing the dye precursor and farther from the support than the layer containing the dye precursor, wherein the layer containing the protease substrate further contains a development center-forming substance. Further, a set of protease detection materials and a method for measuring protease using the above-described protease detection material are provided. A protease detection material, a set of protease detection materials, and a method of measuring protease which allow protease activity to be measured promptly with high sensitivity, and that allow, at the same time, morphological observation of tissues and cells on a thin film to be performed easily.

  本发明提供了一种蛋白酶检测材料，在支撑体上至少具有一层含有染料前体的层和一层含有蛋白酶底物的层，该层与含有染料前体的层位于支撑体的同一侧，且比含有染料前体的层远离支撑体，其中含有蛋白酶底物的层进一步含有显影中心形成物质。此外，还提供了一套蛋白酶检测材料以及使用上述蛋白酶检测材料测量蛋白酶的方法。一种蛋白酶检测材料、一组蛋白酶检测材料和一种测量蛋白酶的方法，可快速、高灵敏度地测量蛋白酶活性，同时可方便地对薄膜上的组织和细胞进行形态观察。
• ONE-POT SYNTHESIS OF 1,2,4-TRIAZINES
  作者：Shahnaz Rostamizadeh、Kamran Sadeghi

  DOI：10.1081/scc-120004086

  日期：2002.1.1

  1,2,4-Triazines have been prepared from the one-pot condensation reaction of acid hydrazide (1), ammonium acetate and dicarbonyl compounds (2) on the surface of silica gel in the presence of triethylamine under microwave irradiation.
• NOVEL ONE POT SYNTHESIS OF SUBSTITUTED 1, 2, 4-TRIAZINES
  作者：Rishan Lang Nongkhlaw、Bekington Myrboh

  DOI：10.1515/hc.2006.12.1.67

  日期：2006.1