2-[4-[2-[[2-(1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl)imidazo[1,2-a]pyrazin-3-yl]amino]acetyl]piperazin-1-yl]benzonitrile | 1357568-20-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 2-[4-[2-[[2-(1-propan-2-yl-3,4-dihydro-2H-quinolin-6-yl)imidazo[1,2-a]pyrazin-3-yl]amino]acetyl]piperazin-1-yl]benzonitrile
• CAS: 1357568-20-7
• 化学式: C₃₁H₃₄N₈O
• 分子量: 534.664
• InChiKey: RHZDGFMJYDLAPG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  40
• 可旋转键数：
  6
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  92.8
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• FUSED-IMIDAZOYL COMPOUNDS USEFUL AS ANTIMICROBIAL AGENTS
  申请人：Chan Tin-Yau

  公开号：US20130210816A1

  公开（公告）日：2013-08-15

  The invention relates to fused-imidazoyl compounds of Formula (I): wherein ring A, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , m and n are as defined herein. Also disclosed are pharmaceutical compositions containing the compound of Formula (I) and methods of using the compound of Formula (I) to treat microbial infections.
• US8871929B2
  申请人：——

  公开号：US8871929B2

  公开（公告）日：2014-10-28
• [EN] FUSED-IMIDAZOYL COMPOUNDS USEFUL AS ANTIMICROBIAL AGENTS<br/>[FR] COMPOSÉS D'IMIDAZOYLE FUSIONNÉ UTILES EN TANT QU'AGENTS ANTIMICROBIENS
  申请人：SCHERING CORP

  公开号：WO2012018662A2

  公开（公告）日：2012-02-09

  The invention relates to fused-imidazoyl compounds of Formula (I): wherein ring A, R1, R2, R3, R4, R5, R6, R7, R8, R9, m and n are as defined herein. Also disclosed are pharmaceutical compositions containing the compound of Formula (I) and methods of using the compound of Formula (I) to treat microbial infections.