3,7-di(piperidin-1-yl)-2,4,6,8-tetraoxa-3,7-diphospha-1,5(1,4)-dibenzenacyclooctaphane | 863650-16-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 3,7-di(piperidin-1-yl)-2,4,6,8-tetraoxa-3,7-diphospha-1,5(1,4)-dibenzenacyclooctaphane
• CAS: 863650-16-2
• 化学式: C₂₂H₂₈N₂O₄P₂
• 分子量: 446.423
• InChiKey: XJTDWJNBJFVOFC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.34
• 重原子数：
  30.0
• 可旋转键数：
  2.0
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  43.4
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  3,7-di(piperidin-1-yl)-2,4,6,8-tetraoxa-3,7-diphospha-1,5(1,4)-dibenzenacyclooctaphane 在 sulfur 作用下， 以 二氯甲烷 为溶剂， 反应 40.0h， 以30%的产率得到cyclobis(O,O'-1,4-phenylenephosphoropiperididothioate)
  参考文献：
  名称：

  Dismutation of Bisphosphorylated Aromatic Diols

  摘要：

  The first study of the dismutation of aromatic diol bisdiantidophosphites has been performed. Derivatives of condensed aromatic systems dismutate more rapidly than their mononuclear analogues. Amide derivatives with aliphatic substituents at the nitrogen atom undergo dismutation more readily than their heterocyclic analogues. In methylene chloride, the process proceeded most rapidly regardless of the aromatic component and the substititent at the phosphorus atom. Apolar solvents (benzene and diethyl ether) did not favor the dismutation. Temperature had no effect oil the time of dismutation, and a catalyst decreased it by a factor of 1.5-2.

  DOI：

  10.1080/104265090517244
• 作为产物：
  描述：

  以 乙腈 为溶剂， 反应 2304.0h， 生成 3,7-di(piperidin-1-yl)-2,4,6,8-tetraoxa-3,7-diphospha-1,5(1,4)-dibenzenacyclooctaphane 、 亚磷酸三酰哌啶
  参考文献：
  名称：

  Dismutation of arylene phosphorodiamidites: Specific features and aspects of preparative use

  摘要：

  The dismutation ofarylene phosphorodiamidites derived from the simplest phenols and naphthols and of their dibasic analogs was studied. The main regular trends of this process and the limits of its synthetic applicability were determined.

  DOI：

  10.1134/s1070363206020046