1,1-Dimethylethyl 4-(3,4-dihydro-2H-1,4-benzoxazin-6-yl)-1-piperazinecarboxylate | 625394-72-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 1,1-Dimethylethyl 4-(3,4-dihydro-2H-1,4-benzoxazin-6-yl)-1-piperazinecarboxylate
• 英文别名: tert-butyl 4-(3,4-dihydro-2H-1,4-benzoxazin-6-yl)piperazine-1-carboxylate
• CAS: 625394-72-1
• 化学式: C₁₇H₂₅N₃O₃
• 分子量: 319.4
• InChiKey: ZHNZEABRBYUUEW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  54
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• BENZOXAZINE DERIVATIVES AS 5-HT6 MODULATORS AND USES THEREOF
  申请人：F. Hoffmann-La Roche AG

  公开号：EP1506179A1

  公开（公告）日：2005-02-16
• [EN] BENZOXAZINE DERIVATIVES AS 5-HT6 MODULATORS AND USES THEREOF<br/>[FR] DERIVES DE BENZOXAZINE SERVANT DE MODULATEURS DE 5-HT6 ET LEURS UTILISATIONS
  申请人：HOFFMANN LA ROCHE

  公开号：WO2003095434A1

  公开（公告）日：2003-11-20

  The present invention provides a compound which has 5-HT6 receptor affinity of the formula (I): a pharmaceutically acceptable salt or a prodrug thereof, where R1, R2, R3, R4, R5, R6, R7, R8, R9, Y, Z1, m, n, and p are as defined herein. The present invention also provides compositions comprising, methods for using, and methods for preparing Compound of Formula (I).