1-methylpropyl propyl carbonate | 151169-42-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: 1-methylpropyl propyl carbonate
• 英文别名: sec-Butyl propyl carbonate；butan-2-yl propyl carbonate
• CAS: 151169-42-5
• 化学式: C₈H₁₆O₃
• 分子量: 160.213
• InChiKey: LPUFIUFFOWNQJP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Catechol protected levodopa diester prodrugs, compositions, and methods of use
  申请人：Xiang Jia-Ning

  公开号：US20080171789A1

  公开（公告）日：2008-07-17

  Catechol protected levodopa diester prodrugs pharmaceutical, compositions comprising catechol protected levodopa diester prodrugs, and methods of using such prodrugs and pharmaceutical compositions for treating diseases such as Parkinson's disease are provided.

  提供了一种保护左旋多巴二酯前药的制药品，包括含有保护左旋多巴二酯前药的制剂，以及利用这种前药和制药组合物治疗帕金森病等疾病的方法。
• PRODRUGS OF FUSED HETEROCYCLIC INHIBITORS OF D-AMINO ACID OXIDASE
  申请人：Heffernan Michele L. R.

  公开号：US20110034434A1

  公开（公告）日：2011-02-10

  The invention relates to prodrugs of fused heterocyclic inhibitors of D-amino oxidase (DAAO) and methods of treating diseases and conditions, wherein modulation of D-amino acid oxidase activity, D-serine levels, D-serine oxidative products and NMDA receptor activity in the nervous system of a mammalian subject is effective.

  该发明涉及融合杂环抑制剂的前药，用于治疗疾病和病况的方法，其中在哺乳动物主体的神经系统中调节D-氨基酸氧化酶活性、D-丝氨酸水平、D-丝氨酸氧化产物和NMDA受体活性是有效的。
• LEVODOPA DIMETHYL-SUBSTITUTED DIESTER PRODRUGS, COMPOSITIONS, AND METHODS OF USE
  申请人：XenoPort, Inc.

  公开号：EP2125702A1

  公开（公告）日：2009-12-02
• HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHOLOGICAL DISORDERS
  申请人：Alkermes Pharma Ireland Limited

  公开号：EP2445502B1

  公开（公告）日：2017-06-21
• Cosmetic composition comprising at least one volatile carbonic acid ester
  申请人：Fouron Jean-Yves

  公开号：US20080161394A1

  公开（公告）日：2008-07-03

  The present application relates to a cosmetic composition comprising at least one carbonic acid ester corresponding to formula (I) below: R1—O—CO—O—R2   (I) in which R1 and R2 are identical or different and represent a linear or branched hydrocarbon-based radical, with the proviso that: when R1 and R2 are linear, they each contain from 1 to 6 carbon atoms, with 6≦R1+R2≦7; and when R1 and/or R2 are branched, they each contain from 1 to 8 carbon atoms, with 6≦R1+R2≦9. This composition can be used as a product for caring for and/or making up keratin materials, in particular the skin, the lips and/or the integuments.