| 880145-69-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• CAS: 880145-69-7
• 化学式: C₅₅H₆₂N₂O₁₄
• 分子量: 975.102
• InChiKey: RZNUSBZZIIYWEQ-UHFFFAOYSA-N

物化性质

• 沸点：
  1005.5±65.0 °C(Predicted)
• 密度：
  1.208±0.06 g/cm3(Predicted)

反应信息

• 作为反应物：
  描述：

  在 吡啶 、 一水合肼 、 溶剂黄146 作用下， 以81%的产率得到
  参考文献：
  名称：

  Synthesis of linked triple helical DNAs possessing high affinity to triple helical DNA binding protein

  摘要：

  The synthesis of triplexes possessing an anthraquinonyl roup and composed of branched oligonucleotides (ONs) is described. Binding ability of a triplex-binding protein (MBP-LOR3(ARF)) to the triplexes was evaluated by an electrophoretic mobility shift assay (EMSA). It was found that the triplex, which has an anthraquinonecarbonyl group at the 5'-end of the third strand and is connected with the pentaerythritol linker, has greater affinity to the protein than an unmodified triplex. (C) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.11.036
• 作为产物：
  描述：

  4-Oxo-pentanoic acid 4-(3-{4-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-butylcarbamoyloxy}-2,2-bis-hydroxymethyl-propoxycarbonylamino)-butyl ester 、 苯甲酰氯 在 吡啶 作用下， 生成 Benzoic acid 3-{4-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-butylcarbamoyloxy}-2-hydroxymethyl-2-[4-(4-oxo-pentanoyloxy)-butylcarbamoyloxymethyl]-propyl ester 、
  参考文献：
  名称：

  Synthesis of linked triple helical DNAs possessing high affinity to triple helical DNA binding protein

  摘要：

  The synthesis of triplexes possessing an anthraquinonyl roup and composed of branched oligonucleotides (ONs) is described. Binding ability of a triplex-binding protein (MBP-LOR3(ARF)) to the triplexes was evaluated by an electrophoretic mobility shift assay (EMSA). It was found that the triplex, which has an anthraquinonecarbonyl group at the 5'-end of the third strand and is connected with the pentaerythritol linker, has greater affinity to the protein than an unmodified triplex. (C) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2005.11.036