[(E)-1-(3-Allyl-cyclohex-2-enyloxy)-penta-1,4-dienyloxy]-triisopropyl-silane | 645421-61-0

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: [(E)-1-(3-Allyl-cyclohex-2-enyloxy)-penta-1,4-dienyloxy]-triisopropyl-silane
• CAS: 645421-61-0
• 化学式: C₂₃H₄₀O₂Si
• 分子量: 376.655
• InChiKey: KHUIUOVURGZYAP-XQNSMLJCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.67
• 重原子数：
  26.0
• 可旋转键数：
  11.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  18.46
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  [(E)-1-(3-Allyl-cyclohex-2-enyloxy)-penta-1,4-dienyloxy]-triisopropyl-silane 在 三甲基氯硅烷 、 双(三甲基硅烷基)氨基钾 作用下， 以 甲苯 为溶剂， 生成
  参考文献：
  名称：

  A sequential Claisen/ring-closing metathesis approach to the synthesis of spirocyclic cyclopentanes and cyclohexanes

  摘要：

  A new method for the formation of spirocycles is described using a sequential Ireland-Claisen/Metathesis strategy to construct spirocyclic systems. Optimization of the Ireland-Claisen conditions provides the key metathesis substrates. The metathesis reactions were highly regioselective by virtue of steric hindrance in the substrate olefins. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2003.09.190
• 作为产物：
  描述：

  3-allylcyclohex-2-en-1-ol 在 双(三甲基硅烷基)氨基钾 作用下， 生成 [(E)-1-(3-Allyl-cyclohex-2-enyloxy)-penta-1,4-dienyloxy]-triisopropyl-silane
  参考文献：
  名称：

  A sequential Claisen/ring-closing metathesis approach to the synthesis of spirocyclic cyclopentanes and cyclohexanes

  摘要：

  A new method for the formation of spirocycles is described using a sequential Ireland-Claisen/Metathesis strategy to construct spirocyclic systems. Optimization of the Ireland-Claisen conditions provides the key metathesis substrates. The metathesis reactions were highly regioselective by virtue of steric hindrance in the substrate olefins. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2003.09.190