2,4-bis(4-dimethylamino-2-methylquinolin-6-yl)amino-6-[1-(2-dipropylaminoethyl)piperazin-4-yl]-[1,3,5]triazine | 462650-50-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 2,4-bis(4-dimethylamino-2-methylquinolin-6-yl)amino-6-[1-(2-dipropylaminoethyl)piperazin-4-yl]-[1,3,5]triazine
• 英文别名: 6-N-[4-[[4-(dimethylamino)-2-methylquinolin-6-yl]amino]-6-[4-[2-(dipropylamino)ethyl]piperazin-1-yl]-1,3,5-triazin-2-yl]-4-N,4-N,2-trimethylquinoline-4,6-diamine
• CAS: 462650-50-6
• 化学式: C₃₉H₅₄N₁₂
• 分子量: 690.938
• InChiKey: DGEUISGYFLNFQC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.4
• 重原子数：
  51
• 可旋转键数：
  14
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  105
• 氢给体数：
  2
• 氢受体数：
  12

文献信息

• Chemical derivatives and their application as antitelomerease agent
  申请人：——

  公开号：US20030087931A1

  公开（公告）日：2003-05-08

  The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which is quite specific. It also relates to novel chemical compounds as well as their therapeutic application in humans.

  本发明涉及癌症治疗和具有相当特异作用机制的新型抗癌药物。它还涉及新型化合物以及它们在人类中的治疗应用。
• Chemical derivatives and their application as antitelomerase agents
  申请人：Mailliet Patrick

  公开号：US20050070571A1

  公开（公告）日：2005-03-31

  The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which is quite specific. It also relates to novel chemical compounds as well as their therapeutic application in humans.

  本发明涉及癌症治疗和具有相当特异作用机制的新型抗癌剂。它还涉及新型化学化合物以及它们在人类治疗方面的治疗应用。
• CHEMICAL DERIVATIVES AND THEIR APPLICATION AS ANTITELOMERASE AGENTS
  申请人：MAILLIET Patrick

  公开号：US20090226411A1

  公开（公告）日：2009-09-10

  The present invention relates to cancer therapy and to novel anticancer agents having a mechanism of action which is quite specific. It also relates to novel chemical compounds as well as their therapeutic application in humans.

  本发明涉及癌症治疗以及具有相当特异作用机制的新型抗癌剂。它还涉及新型化学化合物以及它们在人类治疗中的治疗应用。
• US6887873B2
  申请人：——

  公开号：US6887873B2

  公开（公告）日：2005-05-03
• US7482352B2
  申请人：——

  公开号：US7482352B2

  公开（公告）日：2009-01-27