6-Chlor-7-methyl-3,4-dihydro-benzo-1,2,4-thiadiazin-1,1-dioxid | 3083-60-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻二嗪
• 英文名称: 6-Chlor-7-methyl-3,4-dihydro-benzo-1,2,4-thiadiazin-1,1-dioxid
• 英文别名: 6-chloro-7-methyl-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide；6-chloro-7-methyl-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine 1,1-dioxide；6-chloro-7-methyl-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine 1,1-dioxide
• CAS: 3083-60-1
• 化学式: C₈H₉ClN₂O₂S
• 分子量: 232.691
• InChiKey: PSWWCBUOKPVUID-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  66.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• STABLE PHARMACEUTICAL COMPOSITIONS
  申请人：Komireddi Reddy Prakash

  公开号：US20070116756A1

  公开（公告）日：2007-05-24

  A pharmaceutical dosage form, comprising an outer capsule containing at least one capsule, tablet, and/or particles comprising different drug substances.
• Compositions of stabilized ramipril in combination with another active agent
  申请人：Wilson S. Edward

  公开号：US20070116762A1

  公开（公告）日：2007-05-24

  A pharmaceutical composition comprising ramipril, another active agent, and a blending agent, wherein in the ramipril is coated by the blending agent, and wherein the blending agent is glyceryl behenate, glyceryl stearate, stearyl alcohol, macrogol stearate ether, palmitosearate, ethylene glycol, polyethylene glycol, stearic acid, cetyl alcohol, lauryl alcohol, amylopectin, poloxymer or combinations thereof.
• COMPOSITIONS AND METHODS COMPRISING A THIAZIDE DIURETIC AND A MINERALOCORTICOID INHIBITOR
  申请人：Solomon Lawrence

  公开号：US20070287690A1

  公开（公告）日：2007-12-13

  The invention relates to low dose combinations of a thiazide diuretic and a mineralocorticoid inhibitor and methods for the treatment of hypertension and related disorders. Methods and compositions for administering a thiazide diuretic, such as chlorthalidone, and an mineralocorticoid inhibitor such as spironolactone or eplerenone in a dose range of between 3 mg and 12 mg or eplerenone in a dose range of between 3 mg and 25 mg each,