bis(2-thienyl)amine | 1233325-49-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 英文名称: bis(2-thienyl)amine
• 英文别名: di(2-thienyl)amine；dithiophenylamine；dithienylamine；N-thiophen-2-ylthiophen-2-amine
• CAS: 1233325-49-9
• 化学式: C₈H₇NS₂
• 分子量: 181.282
• InChiKey: RDKXVDSORKHYLX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  68.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-溴噻吩 在 L-精氨酸 、 potassium hydroxide 作用下， 以 水 为溶剂， 80.0 ℃ 、101.33 kPa 条件下， 反应 5.0h， 以76%的产率得到bis(2-thienyl)amine
  参考文献：
  名称：

  磁性MOF催化芳基卤化物和精氨酸的多米诺反应选择性合成二芳胺的绿色温和方法

  摘要：

  AbstractEfficient and selective direct synthesis of diarylamines from aryl halides and arginine as a nitrogen‐donor reagent is reported. Arginine, which is an oral supplement, acts as a useful nitrogen source donor in the copper‐catalyzed reaction. Fe3O4/Cu3(BTC)2, which was easily separated and recycled with a magnet, improved the rate and facilitation of the synthesis of diarylamines selectively. The introduction of a new and available N‐source, simple magnetic separation process, normal atmospheric conditions, and excellent yields under mild reaction conditions are other important features of this work.

  DOI：

  10.1002/hc.21450

文献信息

• [EN] 2, 3, 6-TRISUBSTITUTED-4-PYRIMIDONE DERIVATIVES<br/>[FR] DERIVES DE 2,3,6-TRISUBSTITUE 4-PYRIMIDONE
  申请人：MITSUBISHI PHARMA CORP

  公开号：WO2004085408A1

  公开（公告）日：2004-10-07

  A pyrimidone derivative having tau protein kinase 1 inhibitory activity which is represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof; useful for prventive and/or therapeutic treatment of diseass such as neurodegenerative diseases (e.g. Alzheimer disease); wherein Q represents CH or nitrogen atom; R represents a C1-C12 alkyl group; the ring of Formula (I): represents piperazine ring or piperidine ring; each X independently represents a C1-C8 alkyl group, an optionally partially hydrogenated C6-C10 aryl ring, an indan ring or the like; m represents an integer of 1 to 3; each Y independently represents a halogen atom, a hydroxy group, a cyano group, a C1-C6 alkyl group or the like; n represents an integer of 0 to 8; when X and Y or two Y groups are attached on the same carbon atom, they may combine to each other to form a C2-C6 alkylene group.

  一种具有tau蛋白激酶1抑制活性的嘧啶酮衍生物，其由化学式（I）或其盐、溶剂合物或水合物表示；用于预防和/或治疗神经退行性疾病（例如阿尔茨海默病）；其中Q代表CH或氮原子；R代表C1-C12烷基基团；化学式（I）的环：代表哌嗪环或哌啶环；每个X独立地代表C1-C8烷基基团、可选择性部分氢化的C6-C10芳环、茚环或类似物；m代表1到3的整数；每个Y独立地代表卤素原子、羟基、氰基、C1-C6烷基基团或类似物；n代表0到8的整数；当X和Y或两个Y基团连接在同一碳原子上时，它们可以结合形成C2-C6烷基基团。
• COMPOUND HAVING INDENOACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE
  申请人：Hodogaya Chemical Co., Ltd.

  公开号：US20150249218A1

  公开（公告）日：2015-09-03

  An organic compound with excellent characteristics excelling in hole injecting and transporting performance and having an electron-blocking ability, high stability in a thin film state and excellent heat resistance is provided as a material for an organic electroluminescent device of high efficiency and high durability, and the organic electroluminescent device of high luminous efficiency and high durability is provided using this compound. The compound of a general formula (1) having an indenoacridan ring structure is used as a constituent material of at least one organic layer in the organic electroluminescent device that includes a pair of electrodes and one or more organic layers sandwiched between the pair of electrodes.

  提供一种具有出色的孔注入和传输性能、具有阻挡电子的能力、在薄膜状态下具有高稳定性和优异的耐热性的有机化合物，作为高效和高耐久性的有机电致发光器件的材料，并且使用该化合物提供具有高发光效率和高耐久性的有机电致发光器件。所述通式（1）的化合物具有茚并蒽环结构，作为至少一个有机层的组成材料，用于包括一对电极和一对电极之间夹有一个或多个有机层的有机电致发光器件。
• CHARGE CONTROLLING AGENT AND TONER USING SAME
  申请人：Yasumura Masateru

  公开号：US20120315576A1

  公开（公告）日：2012-12-13

  The present invention provides a charge control agent containing, as an active substance(s), one or two or more rhodanine compounds represented by the following formula (1). where R1 represents a hydrogen atom, etc.; R2 represents a hydrogen atom, a linear or branched alkyl group having 1 to 8 carbon atoms which may have a substituent, a substituted or unsubstituted heterocyclic group, etc.; R3 to R7, which may be identical to or different from each other, represent a hydrogen atom, a linear or branched alkyl group having 1 to 10 carbon atoms which may have a substituent, a linear or branched alkyloxy group having 1 to 20 carbon atoms which may have a substituent, etc., and may be joined to each other to form a ring; and V, W, X, Y and Z represent a carbon atom or a nitrogen atom, and 0 to 3 of any of V, W, X, Y and Z are nitrogen atoms which do not have the substituents of R3 to R7.

  本发明提供了一种包含以下式（1）所表示的一种或两种或更多罗丹宁化合物作为活性物质的电荷控制剂。其中R1代表氢原子等；R2代表氢原子、具有1至8个碳原子的线性或支链烷基基团，该基团可能具有取代基，取代或未取代的杂环基团等；R3至R7（它们可以相同也可以不同）代表氢原子、具有1至10个碳原子的线性或支链烷基基团，该基团可能具有取代基，具有1至20个碳原子的线性或支链烷氧基基团，该基团可能具有取代基等，并且它们可以相互连接形成环；V、W、X、Y和Z代表碳原子或氮原子，V、W、X、Y和Z中的任意0至3个是不具有R3至R7的取代基的氮原子。
• PROCESS FOR PRODUCING A CHARGE CONTROL AGENT
  申请人：HODOGAYA CHEMICAL CO., LTD.

  公开号：US20140171628A1

  公开（公告）日：2014-06-19

  A process for producing a charge control agent comprising an azo-based iron complex salt compound as an effective component, comprises: synthesizing a monoazo compound through diazotization coupling; and ironing the monoazo compound by using an ironizing agent such as ferric chloride to produce an azo-based iron complex salt compound represented by the following formula. The ironization reaction of the monoazo compound is carried out while pH is kept at 7.0 to 8.0. Since the above azo-based iron complex salt compound having high purity can be obtained at a high yield, it can be used as a charge control agent directly and a special purification step can be eliminated, thereby making it possible to greatly cut the production cost.

  生产电荷控制剂的方法包括将基于偶氮的铁络合盐化合物作为有效成分，包括：通过重氮化偶联合成单偶氮化合物；并使用铁化剂（如氯化铁）对单偶氮化合物进行铁化，以产生以下公式所代表的基于偶氮的铁络合盐化合物。在保持pH值为7.0至8.0的情况下进行单偶氮化合物的铁化反应。由于上述高纯度的基于偶氮的铁络合盐化合物可以以高收率获得，因此可以直接用作电荷控制剂，并且可以消除特殊的纯化步骤，从而大大降低生产成本。
• COMPOUND HAVING ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE
  申请人：Yokoyama Norimasa

  公开号：US20130075715A1

  公开（公告）日：2013-03-28

  An organic compound with characteristics excelling in hole-injecting/transporting performance and having an electron blocking ability, a highly stable thin-film state, and excellent heat resistance is provided as material for an organic electroluminescent device of high efficiency and high durability, and the organic electroluminescent device of high efficiency and high durability is provided using this compound. The compound of a general formula (Chemical Formula 1) having a substituted acridan ring structure is used as a constituent material of at least one organic layer in the organic electroluminescent device that includes a pair of electrodes and one or more organic layers sandwiched between the pair of electrodes.

  提供一种具有出色的注入/输运孔特性、具有电子阻挡能力、高度稳定的薄膜状态和出色的耐热性的有机化合物，作为高效和高耐久性的有机电致发光器件的材料，并且使用该化合物提供高效和高耐久性的有机电致发光器件。通用式（化学式1）的化合物具有取代花菁环结构，作为至少一个有机层的构成材料，该有机层包括一对电极和夹在电极对之间的一个或多个有机层的有机电致发光器件。