2-[(2-Imino-3,3-dimethyl-7-piperazin-1-ylpyrrolo[3,2-b]pyridin-1-yl)methyl]benzonitrile | 1314944-62-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 2-[(2-Imino-3,3-dimethyl-7-piperazin-1-ylpyrrolo[3,2-b]pyridin-1-yl)methyl]benzonitrile
• CAS: 1314944-62-1
• 化学式: C₂₁H₂₄N₆
• 分子量: 360.462
• InChiKey: XVFXSUWGNFQNKI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  79
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• [EN] FUSED PYRIDINE DERIVATIVES<br/>[FR] DÉRIVÉS DE PYRIDINE CONDENSÉS
  申请人：KBP BIOMEDICAL CO LTD

  公开号：WO2011085643A1

  公开（公告）日：2011-07-21

  Fused pyridine derivatives shown as the general formula (I), and their pharmaceutically acceptable salts, stereoisomers or solvates thereof are disclosed, which belong to the technical field of medicines. The R1, R2, R3, Q, X and Y substituents in formula (I) are defined as in the description. Also disclosed are the preparation methods, pharmaceutical compositions and uses of the compounds in the manufacture of the medicine for the treatment and/or prevention of noninsulin-dependent diabetes, hyperglycemia, hyperlipidemia and insulin resistance.