(3-methyl-tetrahydropyran-3-yl)-thiophene-2-carboxylate | 1131665-18-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 英文名称: (3-methyl-tetrahydropyran-3-yl)-thiophene-2-carboxylate
• 英文别名: (3-Methyloxan-3-yl) thiophene-2-carboxylate；(3-methyloxan-3-yl) thiophene-2-carboxylate
• CAS: 1131665-18-3
• 化学式: C₁₁H₁₄O₃S
• 分子量: 226.296
• InChiKey: AKEANTMEDNURAR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  63.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  4-甲基-4-戊烯醇 、 lead(IV) tetra(thiophene-2-carboxylate) 以 三氟甲苯 为溶剂， 反应 0.75h， 以68%的产率得到(3-methyl-tetrahydropyran-3-yl)-thiophene-2-carboxylate
  参考文献：
  名称：

  Acyloxyetherifications mediated by lead tetracarboxylates

  摘要：

  Lead(IV) tetricarboxylates ire capable of reacting With Unsaturated alcohols to give the products of cyclic acyloxyetherification, usually as a mixture of tetrahydro-2H-pyranyl and tetrahydrofuranyt compounds. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.12.071

文献信息

• Acyloxyetherifications mediated by lead tetracarboxylates
  作者：Ian F. Cottrell、Mark G. Moloney、Kirsty Smithies

  DOI：10.1016/j.tetlet.2008.12.071

  日期：2009.3

  Lead(IV) tetricarboxylates ire capable of reacting With Unsaturated alcohols to give the products of cyclic acyloxyetherification, usually as a mixture of tetrahydro-2H-pyranyl and tetrahydrofuranyt compounds. (C) 2008 Elsevier Ltd. All rights reserved.