Triethoxy-[3-[4-(piperidin-1-ylmethyl)triazol-1-yl]propyl]silane | 1548801-33-7

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: Triethoxy-[3-[4-(piperidin-1-ylmethyl)triazol-1-yl]propyl]silane
• 英文别名: triethoxy-[3-[4-(piperidin-1-ylmethyl)triazol-1-yl]propyl]silane
• CAS: 1548801-33-7
• 化学式: C₁₇H₃₄N₄O₃Si
• 分子量: 370.567
• InChiKey: RILYFBUKHWKSLK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  25
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  61.6
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  3-氯丙基三乙氧基硅烷 在 sodium azide 、 溴化三(三苯基磷)铜 、 三乙胺 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 生成 Triethoxy-[3-[4-(piperidin-1-ylmethyl)triazol-1-yl]propyl]silane
  参考文献：
  名称：

  Synthesis of polyfunctional triethoxysilanes by ‘click silylation’

  摘要：

  The copper-catalyzed 'click silylation' has been exploited for the chemical modification of gamma-azidopropyltriethoxysilane (AzPTES) with a wide range of terminal alkynes (la-lv) in a one-pot operation. The novel 1,2,3-triazole-triethoxysilane derivatives (2a-2v) were synthesized by this procedure and comprehensively characterized by IR spectra, H-1 and C-13 NMR, and HRMS studies. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.12.037

文献信息

• Synthesis of polyfunctional triethoxysilanes by ‘click silylation’
  作者：Gurjaspreet Singh、Satinderpal Singh Mangat、Jandeep Singh、Aanchal Arora、Ramesh K. Sharma

  DOI：10.1016/j.tetlet.2013.12.037

  日期：2014.1

  The copper-catalyzed 'click silylation' has been exploited for the chemical modification of gamma-azidopropyltriethoxysilane (AzPTES) with a wide range of terminal alkynes (la-lv) in a one-pot operation. The novel 1,2,3-triazole-triethoxysilane derivatives (2a-2v) were synthesized by this procedure and comprehensively characterized by IR spectra, H-1 and C-13 NMR, and HRMS studies. (C) 2013 Elsevier Ltd. All rights reserved.